Evidence map›Paper›PMID 42219412›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026

A brief novel questionnaire to estimate premorbid functional state in acute stroke patients.

Askiel Bruno, Giandor Saltz, Matthew L Abbott, Mithilesh Siddu, Aisha Naushad, Vetriganesh Maduraiveeran, Justin Skariah, Kareena Udeshi, Saad Tanzeem, Bruno Quevedo-Tejada and 3 more

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Askiel BrunoDepartment of Neurology, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, Georgia. abruno@augusta.edu.ORCID http://orcid.org/0000-0003-0133-585X
Giandor SaltzDepartment of Neurology, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, Georgia.
Matthew L AbbottDepartment of Neurology, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, Georgia.
Mithilesh SidduDepartment of Neurology, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, Georgia.
Aisha NaushadMedical College of Georgia, Augusta University, Augusta , Georgia.
Vetriganesh MaduraiveeranMedical College of Georgia, Augusta University, Augusta , Georgia.
Justin SkariahMedical College of Georgia, Augusta University, Augusta , Georgia.
Kareena UdeshiMedical College of Georgia, Augusta University, Augusta , Georgia.
Saad TanzeemMedical College of Georgia, Augusta University, Augusta , Georgia.
Bruno Quevedo-TejadaMedical College of Georgia, Augusta University, Augusta , Georgia.
Adarshini RajaMedical College of Georgia, Augusta University, Augusta , Georgia.
Kevin DobbinDepartment of Biostatistics, Data Science & Epidemiology, School of Public Health, Augusta University, Augusta, Georgia.
Fenwick T NicholsDepartment of Neurology, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring acute stroke evaluation, knowing a patient's premorbid functional state can guide clinical decision and research considerations. The often-utilized modified Rankin scale was not designed and is not well suited for this purpose. Thus, we developed and tested a brief questionnaire to assess a patient's premorbid functional state.

methodsThe novel questionnaire scores range from 0 to 5. Scores 0-2 represent increasing degrees of independent functioning, not at all difficult (0), somewhat difficult (1), and very difficult (2). Scores 3, 4, and 5 represent moderate to severe disabilities. Paired raters independently tested the novel questionnaire on two consecutive days in patients with acute cerebrovascular events. The kappa statistic evaluated reliability of the novel questionnaire and previously established questionnaires were used for concurrent validity testing.

resultsIn 76 patients, mean age 77 (SD 14) years and 51% women, the overall agreement between the paired raters was 79%. The standard kappa was 0.62 (95% CI 0.47-0.76), p < 0.001, and the weighted kappa was 0.89 (95% CI 0.82-0.96), p < 0.001. The novel questionnaire scores correlated well with the Groningen scale (r = 0.70 and r = 0.67 for the two raters, p < 0.001 for both), and with the Lawton scale (r = -0.77 and r= -0.82 for the two raters, p < 0.001 for both).

conclusionsThis novel brief baseline function questionnaire for assessing a patient's premorbid functional state has acceptable clinimetric properties and could be used to rapidly and reliably score the premorbid baseline function among acute stroke patients.

Indexed as

Functional StatusStrokeAgedAged, 80 and overDisability EvaluationFemaleHumansMaleMiddle AgedReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesActivities of daily livingDisabilitiesFunctional stateStroke

Identifiers

PMID42219412
PMCPMC13222895

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.