Trial reportThe Journal of international medical research2026
Effect of injectable platelet-rich fibrin on orthodontically induced apical root resorption following non-extraction-based orthodontic treatment in adults: A randomized controlled clinical trial.
Trial report in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveTo investigate the effect of repeated submucosal administration of injectable platelet-rich fibrin in the buccal region of the lower incisors on orthodontically induced apical root resorption in patients with moderate crowding.MethodsThirty-six patients (8 males and 28 females; mean age, 20.22 ± 2.55 years) with Class l malocclusion and moderate mandibular incisors crowding (4-6 mm) were included. Participants were randomly assigned to the control or 4-time injectable platelet-rich fibrin group. Fixed orthodontic treatment was performed, and the injection was administered directly after bonding the mandibular brackets during four sessions conducted at 28-day intervals. The orthodontically induced root resorption was assessed using cone-beam computed tomography images by measuring the root length.ResultsAll 36 patients completed the orthodontic treatment. The average root resorption of the lower incisors was 0.53 ± 0.09 mm (
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