Evidence map›Paper›PMID 42218755›Full record

Trial reportJournal of the International Society of Sports Nutrition2026

Selected immunoendocrine and performance adaptations to upper-body plyometric training and β-alanine supplementation in male swimmers.

Hui Gao, Xuemei Yu, Zhiyong Guo

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Hui GaoSchool of Physical Education, Xi'an University of Finance and Economics, Xi'an, People's Republic of China.
Xuemei YuSchool of Physical Education, Xi'an University of Finance and Economics, Xi'an, People's Republic of China.
Zhiyong GuoSchool of Physical Education, Xi'an University of Finance and Economics, Xi'an, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpper-body plyometric training (PT) enhances neuromuscular performance and power production. However, its application in swimming and its potential interaction with β-alanine (BA) supplementation remain largely unexplored. Therefore, this study investigated the combined effects of upper-body PT and BA supplementation on performance and immunoendocrine adaptations in trained male swimmers.

methodsThirty trained male swimmers (age: 25.7 ± 2.6 years; height: 1.83 ± 0.07 m; body mass: 81.6 ± 3.2 kg) were randomly assigned to one of three groups: PT + BA, PT + placebo (PL), or control (CON). Participants in the PT groups completed an 8-week upper-body PT program (2 sessions·week⁻¹). Each session consisted of upper-body plyometric exercises performed for 3-4 sets of 12-16 repetitions with 120 s rest between sets. Participants in the supplementation groups ingested β-alanine (4.8 g·day⁻¹ divided into six 0.8 g doses) or a matched placebo daily throughout the intervention. Assessments conducted before and after the intervention included medicine ball throw (MBT), push-up endurance, one-repetition maximum (1RM) bench press, swim ergometer peak and mean power output (PPO and MPO), and 50-, 100-, and 200-m freestyle performance. Blood samples were also collected pre- and post-intervention to determine testosterone, cortisol, and immunoglobulin A (IgA) concentrations.

resultsBoth PT groups showed significant improvements in all performance outcomes compared with baseline (all p < 0.05), with effect sizes ranging from small to moderate. Post hoc analyses revealed a significant group × time interaction for MBT (p = 0.045), push-up endurance (p = 0.041), PPO (p = 0.026), and MPO (p = 0.033), indicating greater improvements in the PT + BA group than in the PT + PL group. In addition, following the training intervention, the PT + BA group showed significant changes in testosterone (p = 0.011), cortisol (p = 0.028), and IgA (p = 0.042) concentrations compared with the PT + PL group.

conclusionsEight weeks of upper-body PT significantly enhanced upper-body power, anaerobic capacity, and swimming performance in trained male swimmers. BA supplementation further amplified these training-induced adaptations and promoted a more favorable immunoendocrine adaptation profile. These findings suggest that combining upper-body PT with β-alanine supplementation may provide synergistic benefits for performance development and physiological recovery in competitive swimmers.

Indexed as

Adaptation, PhysiologicalAthletic Performancebeta-AlanineDietary SupplementsPlyometric ExerciseSwimmingAdultHumansHydrocortisoneMalePhysical EnduranceTestosteroneYoung Adultbeta-AlanineHydrocortisoneTestosteronebuffering capacityimmune functionplyometric trainingswimming performanceβ-alanine

Identifiers

PMID42218755
PMCPMC13224686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.