Evidence map›Paper›PMID 42218480›Full record

ReviewBiotechnology for biofuels and bioproducts2026

Wastewater-to-biofuels and bioproducts through integrated anaerobic digestion, bioelectrochemical systems, and algal biorefineries: a systematic review of techno-economic and life-cycle evidence.

Isnanik Juni Fitriyah, Sulistyo Saputro, Sajidan Sajidan

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels and bioproducts, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Isnanik Juni FitriyahUniversitas Sebelas Maret, Surakarta, Indonesia.
Sulistyo SaputroUniversitas Sebelas Maret, Surakarta, Indonesia. sulistyo_s@staff.uns.ac.id.
Sajidan SajidanUniversitas Sebelas Maret, Surakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wastewater management is increasingly shifting from conventional pollution control toward resource recovery systems that support clean water access, renewable energy production, and circular bioeconomy development. This systematic review synthesizes the literature on wastewater-to-biofuels and bioproducts through the integration of anaerobic digestion, bioelectrochemical systems, and algal biorefineries, with particular attention to techno-economic analysis and life-cycle assessment evidence. A systematic literature review was conducted on peer-reviewed studies published between 2005 and 2025, resulting in 90 selected articles that were analyzed through thematic and comparative synthesis. The findings show a clear transition from single-technology optimization toward integrated systems based on the water-energy-nutrient nexus. Anaerobic digestion remains the most mature pathway for organic load reduction and biogas production, while bioelectrochemical systems provide additional opportunities for electricity and hydrogen recovery. Algal biorefineries strengthen nutrient recovery and expand the production of biomass-based bioproducts. Comparative synthesis indicates that integrated systems can outperform single technologies when organic load, nutrient availability, process compatibility, operational scale, and product valorization are aligned. Integration may become counterproductive when additional capital cost, operational complexity, energy demand, or downstream processing burdens exceed the value of recovered resources. The TEA-LCA synthesis demonstrates that technology selection should be guided by trade-offs between economic feasibility and environmental performance rather than by technical efficiency alone. This review contributes a decision-oriented synthesis for selecting single or integrated wastewater-to-biofuels configurations that are technically feasible, economically viable, and environmentally sustainable.

Indexed as

Algal biorefineriesAnaerobic digestionBioelectrochemical systemsTechno-economic and life-cycle assessmentWastewater-to-biofuels

Identifiers

PMID42218480
PMCPMC13430706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.