Anterior capsule polishing prevents anterior capsule fibrosis after phacovitrectomy without intraocular lens implantation.

Xulong Liao, Qi Zhang, Yuqiang Huang, Weiqi Chen, Andrzej Grzybowski, Haoyu Chen

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Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Xulong LiaoJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China.

Qi ZhangJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China.

Yuqiang HuangJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China.

Weiqi ChenJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China.

Andrzej GrzybowskiFoundation for Ophthalmology Development, Institute for Research in Ophthalmology, Poznan, Poland.

Haoyu ChenJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China. haoyuchen@cuhk.edu.hk.

Funding

the Intramural Grant of Joint Shantou International Eye Center 24-008

6 · The paper itself

Abstract

objectiveTo investigate whether anterior capsule polishing can prevent the fibrosis of the anterior capsule in phacovitrectomy without intraocular lens (IOL) implantation. METHODS AND ANALYSIS: A retrospective study including seventy cases of phacovitrectomy without IOL implantation was conducted. Fifty cases received 360-degree anterior capsule polishing, and 20 cases did not receive polishing. The severity of anterior capsule fibrosis was calculated by adding the score (from 0 to 3) of each clock hour. The fibrosis severity was compared in the groups with and without polishing using Mann-Whitney U test. The risk factors of anterior capsule fibrosis were explored using single and multiple linear regression. The location of secondary intraocular lens implantation was compared between the polishing and non-polishing groups with Chi-square test.

resultsThe median severity score of the polishing group was significantly less than that of the non-polishing group (6 vs. 24 out of 36, P < 0.001). Multiple regression showed that diabetes (b = 14.634, P = 0.001), silicone oil tamponade (b = 8.734, P < 0.001), and non-polishing (b = 13.731, P < 0.001) were the risk factors of anterior capsule fibrosis. Anterior capsule polishing was associated with a higher chance of secondary in-the-bag IOL implantation (OR = 4.889, P = 0.004).

conclusionPolishing the anterior capsule is associated with reduced fibrosis of the anterior capsule in phacovitrectomy without primary IOL implantation, and more chance of secondary in-the-bag IOL implantation.

Indexed as

Anterior Capsule of the LensLens Capsule, CrystallinePhacoemulsificationPostoperative ComplicationsVitrectomyAgedFemaleFibrosisHumansLens Implantation, IntraocularMaleMiddle AgedRetrospective StudiesRisk FactorsAnterior capsule fibrosisAnterior capsule polishingPhacovitrectomySecondary IOL implantation

Identifiers

PMID42218440

DOI10.1186/s12886-026-04972-w

PMCPMC13224663

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