Evidence map›Paper›PMID 42218438›Full record

ArticleBMC surgery2026

Effect of controlled hypotension combined with low-pressure tourniquet on hemoglobin reduction after total knee arthroplasty.

Jia Ji, Ming Jiang, Lixin Huang, Huilin Yang, Wu Xu, Yijian Zhang, Dinghua Jiang, Linyan Liu

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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jia Ji *Department of Anesthesiology and Surgery, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China.
Ming Jiang *Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China.
Lixin HuangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China.
Huilin YangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China.
Wu XuDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China. xuwu@suda.edu.cn.
Yijian ZhangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China. zhangyijian@suda.edu.cn.
Dinghua JiangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China. jdhyzjyh@126.com.
Linyan LiuDepartment of Anesthesiology and Surgery, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215006, China. liulinyan01@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood loss is common in total knee arthroplasty (TKA). Tourniquet use and controlled hypotension are standard interventions to minimize intraoperative bleeding and avoid transfusions. This study compared the effects of conventional tourniquet use versus controlled hypotension combined with a low-pressure tourniquet on postoperative hemoglobin reduction in TKA.

methodsIn this single-center retrospective cohort study, 90 patients undergoing unilateral TKA under general anesthesia were assigned to either the conventional tourniquet group (n = 49) or the controlled hypotension-low-pressure tourniquet group (n = 41). Primary outcomes included postoperative red blood cell (RBC) count, hemoglobin levels, reductions in RBC and hemoglobin, drainage volume, estimated total blood loss, and transfusion rate. Secondary outcomes were intraoperative duration, duration of hospitalization, and incidence of lower extremity deep venous thrombosis (DVT).

resultsThe controlled hypotension-low-pressure tourniquet group exhibited higher postoperative RBC count and hemoglobin levels. Reductions in RBC, hemoglobin, and cumulative drainage volume were lower, while estimated total blood loss, transfusion requirements, intraoperative duration, and duration of hospitalization were significantly reduced compared with the conventional tourniquet group. DVT incidence was similar between the two groups.

conclusionControlled hypotension with a low-pressure tourniquet effectively reduced postoperative blood loss without increasing the risk of lower limb DVT.

Indexed as

Arthroplasty, Replacement, KneeBlood Loss, SurgicalHemoglobinsHypotension, ControlledTourniquetsAgedFemaleHumansMaleMiddle AgedRetrospective StudiesHemoglobinsClinical outcomesControlled hypotensionHemoglobin dropTotal knee arthroplastyTourniquet

Identifiers

PMID42218438
PMCPMC13430812

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.