Evidence map›Paper›PMID 42218431›Full record

ArticleBMC psychiatry2026

Machine learning-based prediction of intellectual disability in children with autism spectrum disorder: using behavioral observation techniques.

Xiaolin Liu, Ting Han, Zhongquan Jiang, Lifei Hu, Wenhao Li, Chao Song

Abstract read
In one paragraph

Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolin Liu *Department of Developmental and Behavioral Sciences, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou City, Zhejiang Province, China.
Ting Han *Department of Developmental and Behavioral Sciences, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou City, Zhejiang Province, China.
Zhongquan JiangSchool of Public Health, Lanzhou University, Lanzhou City, Gansu Province, China.
Lifei HuDepartment of Developmental and Behavioral Sciences, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou City, Zhejiang Province, China.
Wenhao LiDepartment of Developmental and Behavioral Sciences, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou City, Zhejiang Province, China.
Chao SongDepartment of Developmental and Behavioral Sciences, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou City, Zhejiang Province, China. songchao1987@zju.edu.cn.

Funding

Natural Science Foundation of Zhejiang Province LTGY24H090005
6 · The paper itself

Abstract

purposeTo construct and evaluate a LightGBM prediction model for intellectual disabilities in children with Autism Spectrum Disorder (ASD).

methodsA total of 384 ASD children who completed the Wechsler Intelligence Test and Adaptive Behavioral Assessment System were included in the analysis. The LightGBM model was trained using behavioral observation data and underwent hyperparameter tuning and feature selection.

resultsAmong the ASD children, 32.9% had comorbid ID. The LightGBM model exhibited the highest sensitivity and accuracy, with values of 0.793 and 0.760, respectively. It also achieved an AUC of 0.747, with overall quality of relationships, unusual sensory interests, and gestures/postures being the top predictive features.

conclusionThe LightGBM model demonstrated strong predictive performance, enabling early identification of comorbid ID in preschool children with ASD and facilitating personalized intervention strategies.

Indexed as

Autism Spectrum DisorderBehavior Observation TechniquesIntellectual DisabilityMachine LearningBoosting Machine Learning AlgorithmsChildChild, PreschoolClassification AlgorithmsComorbidityFemaleHumansMalePrediction AlgorithmsPredictive Learning ModelsAutism spectrum disorderIntellectual disabilitiesLightGBMMachine learningPrediction model

Identifiers

PMID42218431
PMCPMC13445737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.