Evidence map›Paper›PMID 42218412›Full record

Observational studyBMC public health2026

A natural experiment in school lighting: observational evidence linking far-red light exposure to slower myopia progression in Chinese Uyghur schoolchildren.

Chang Liu, Lei Chen, Lanlan Wang, Huijun Shao, Yinling Sang, Qiaoli Li, Yangzong Suolang, Wuqi Chen, Dongwei Liu

Abstract readObservational Study
In one paragraph

Observational study in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Chang Liu *Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Lei Chen *School of Materials Science and Engineering, Hefei University of Technology, Hefei, 230009, China.
Lanlan WangDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Huijun ShaoDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Yinling SangDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Qiaoli LiDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Yangzong SuolangDepartment of Ophthalmology, Shannan People's Hospital of Tibet, Shannan, 856100, China.
Wuqi ChenThe First Clinical Medical College, Anhui Medical University, Hefei, 230032, China.
Dongwei LiuDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China. liudongwei@ahmu.edu.cn.ORCID http://orcid.org/0009-0009-5617-4791

Funding

College Students' Innovation and Entrepreneurship Training Project of Anhui Province S202410366013Key Research and Development Technology project of Anhui Province 2022j11020013Natural Science Foundation for Group-style Medical Aid Project of Tibet Autonomous Region XZZR202402034[W]Natural Science Foundation of Tibet Autonomous Region XZ202501ZR0090the Major Science and Technology Project of Zhongshan City of Guangdong Province on the Strategic Emerging Industries Technology Research Topic 2022A1007the National Natural Science Foundation 21875058the Natural Science Foundation of Anhui Province 2208085J13
6 · The paper itself

Abstract

backgroundChildhood myopia is a growing problem worldwide. In a primary school in Xinjiang, China, some classrooms had been installed with far-red/near-infrared (FR/NIR) lighting, while others kept conventional lights. This natural experiment let us test whether everyday exposure to FR/NIR light is linked to slower myopia progression in Uyghur children-a group often understudied despite high myopia rates.

methodsIn this one-year prospective observational cohort study, we invited all eligible Uyghur children in grades 2 and 3. Exposure groups were defined by pre-existing classroom lighting conditions (FR/NIR-enriched vs. Conventional-lit). Primary outcome was change in axial length (AL); secondary outcome was change in spherical equivalent refraction (SER, calculated as sphere + ½ cylinder). Propensity score matching (PSM) was employed to address confounding, with sensitivity analyses (ANCOVA and IPTW-ANCOVA) conducted to assess robustness.

resultsAfter PSM, 82 participants (41 per group) were included. AL increase was significantly smaller in the FR/NIR-enriched group (0.19 ± 0.09 mm) than Conventional-lit group (0.34 ± 0.12 mm), with a mean difference of -0.15 mm (95% CI: -0.20 to -0.10; P < 0.001). SER myopic shift was also attenuated in the FR/NIR-enriched group (-0.12 ± 0.46 D vs. -0.52 ± 0.59 D), yielding a mean difference of 0.40 D (95% CI: 0.16 to 0.64; P < 0.001). Subgroup analyses suggested age-related differences.

conclusionsOver one year, children in classrooms with FR/NIR-enriched lighting showed slower eye growth and less myopic shift. With careful statistical adjustment, these findings suggest that changing classroom lighting could be a simple, passive way to help control myopia at the population level.

Indexed as

LightingMyopiaSchoolsCentral Asian PeopleChildChinaDisease ProgressionFemaleHumansMaleProspective StudiesRed LightAxial lengthCohort studyFar-red/near-infrared lightMyopiaNon-interventionalUyghur children

Identifiers

PMID42218412
PMCPMC13430845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.