Evidence map›Paper›PMID 42218253›Full record

ArticleCell death and differentiation2026

ALKBH5 aggravates scarring after glaucoma surgery via m

Ting Yu, Fan Yang, Jijingru Yang, Chang Shu, Xitai Zhang, Qin Liu, Yajie Liu, Xin Liang, Min Li, Wenjun Hu and 3 more

Abstract read
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In one paragraph

Article in Cell death and differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ting Yu *Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID http://orcid.org/0009-0000-1927-3437
Fan Yang *Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID http://orcid.org/0000-0003-0010-1752
Jijingru Yang *Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID http://orcid.org/0009-0003-7663-0543
Chang ShuDepartment of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xitai ZhangDepartment of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Qin LiuDepartment of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yajie LiuDepartment of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xin LiangDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai, China.
Min LiDepartment of Ophthalmology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenjun HuDepartment of Blood Transfusion, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. huwenjun@ahmu.edu.cn.ORCID http://orcid.org/0009-0000-9756-5208
Bilian KeDepartment of Ophthalmology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. kebilian@126.com.
Xiaojun ZhaDepartment of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, China. zhaxiaojunpumc@gmail.com.ORCID http://orcid.org/0000-0003-4006-0748
Ning LiDepartment of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China. liningnature@126.com.ORCID http://orcid.org/0000-0002-3326-928X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81500716National Natural Science Foundation of China (National Science Foundation of China) 82403463
6 · The paper itself

Abstract

Glaucoma is a leading cause of irreversible blindness, and for patients unresponsive to medical therapy, glaucoma filtration surgery (GFS) is the primary intervention to lower intraocular pressure (IOP). However, postoperative scarring often leads to surgical failure. Here, we identify RNA demethylase ALKBH5 as a key regulator of fibrotic remodeling after GFS via an epitranscriptomic mechanism involving N6-methyladenosine (m

Identifiers

PMID42218253

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.