Evidence map›Paper›PMID 42218229›Full record

ArticleScientific reports2026

Anti-Candida albicans effect of the new antifungal compound Venetin-1 obtained from earthworms versus amphotericin B.

Kinga Lewtak, Magdalena Dryglewska, Sylwia Mieszawska, Ewa Skwarek, Paulina Czaplewska, Weronika Ścibek-Rejmontowska, Hüseyin Korkmaz, Jerzy Wydrych, Wojciech Kaźmierski, Krzysztof Skrzypiec and 1 more

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kinga LewtakDepartment of Immunobiology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland. kinga.lewtak@mail.umcs.pl.
Magdalena DryglewskaDepartment of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.
Sylwia MieszawskaChair and Department of Medical Microbiology, Collegium Universum, Medical University of Lublin, Lublin, Poland.
Ewa SkwarekDepartment of Radiochemistry and Environmental Chemistry, Institute of Chemical Sciences, Maria Curie-Skłodowska University, Lublin, Poland.
Paulina CzaplewskaIntercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Gdańsk, Poland.
Weronika Ścibek-RejmontowskaIntercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Gdańsk, Poland.
Hüseyin KorkmazIntercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Gdańsk, Poland.
Jerzy WydrychDepartment of Functional Anatomy and Cytobiology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.
Wojciech KaźmierskiBruker Poland Sp. z o.o, Poznań, Poland.
Krzysztof SkrzypiecAnalytical Laboratory, Institute of Chemical Sciences, Maria Curie-Skłodowska University, Lublin, Poland.
Marta J FiołkaDepartment of Immunobiology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland. marta.fiolka@mail.umcs.pl.

Funding

National Science Centre, Poland No. 2020/37/B/NZ7/00763
6 · The paper itself

Abstract

Candida albicans is a commensal organism that can cause disease in individuals with weakened and compromised immune systems. These fungi are responsible for superficial or invasive infections associated with high mortality. The aim of this study was to compare the activity of the new antifungal compound Venetin-1, obtained from the coelomic fluid of the earthworm Dendrobaena veneta, with the effects of the antibiotic amphotericin B (AmB). Flow cytometry, fluorescence microscopy, scanning electron microscopy, atomic force microscopy, and FTIR spectroscopic methods were used for comparative analysis. Venetin-1 at the highest concentration used (100 µg mL

Indexed as

Amphotericin BAntifungal AgentsCandida albicansOligochaetaAnimalsCell WallMicrobial Sensitivity TestsMicroscopy, Electron, ScanningSpectroscopy, Fourier Transform InfraredAmphotericin BAntifungal AgentsAmphotericin BCandida albicansFlow cytometryMicroscopic analysisProteomic analysisVenetin-1

Identifiers

PMID42218229
PMCPMC13457962

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.