Evidence map›Paper›PMID 42218212›Full record

ArticleScientific reports2026

Dental pulp-derived mesenchymal stem cells reduce lesion progression in a rat model of endometriosis.

Ismet Hortu, Gözde Kandemir Demirci, Birant Şimşek, Ebru Eroğlu, Özgün Selim Germiyan, Aylin Gökhan, Dilek Taşkiran, Mehmet Emin Kaval, Uğur Tekin, Pelin Güneri and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ismet HortuDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ege University, 35100, İzmir, Türkiye.
Gözde Kandemir DemirciDepartment of Stem Cell, Institute of Health Sciences, Ege University, 35100, İzmir, Türkiye. gozde.kandemir.demirci@ege.edu.tr.
Birant ŞimşekDepartment of Stem Cell, Institute of Health Sciences, Ege University, 35100, İzmir, Türkiye.
Ebru EroğluDepartment of Histology and Embryology, Faculty of Medicine, Ege University, 35100, İzmir, Türkiye.
Özgün Selim GermiyanDepartment of Stem Cell, Institute of Health Sciences, Ege University, 35100, İzmir, Türkiye.
Aylin GökhanDepartment of Histology and Embryology, Faculty of Medicine, Ege University, 35100, İzmir, Türkiye.
Dilek TaşkiranDepartment of Physiology, Faculty of Medicine, Ege University, 35100, İzmir, Türkiye.
Mehmet Emin KavalDepartment of Endodontology, Faculty of Dentistry, Ege University, 35100, İzmir, Türkiye.
Uğur TekinDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ege University, 35100, İzmir, Türkiye.
Pelin GüneriDepartment of Oral and Maxillofacial Radiology, Faculty of Dentistry, Ege University, 35100, İzmir, Türkiye.
Timur KöseDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Ege University, 35100, İzmir, Türkiye.
Yiğit UyanikgilDepartment of Stem Cell, Institute of Health Sciences, Ege University, 35100, İzmir, Türkiye.

Funding

The Scientific and Technological Research Council of Turkey (TÜBİTAK). Project number: SBAG 224S142
6 · The paper itself

Abstract

Endometriosis is a chronic, estrogen-dependent inflammatory disease sustained by aberrant angiogenesis and progressive fibrosis. We evaluated the therapeutic efficacy of human dental pulp-derived mesenchymal stem cells (DP-MSCs) in a surgically induced rat endometriosis model. Twenty-eight adult female Wistar rats were randomized (n = 7/group) to sham group (G1), untreated endometriosis-group (G2), single-dose DP-MSCs-group (G3) (2 × 10

Indexed as

Dental PulpEndometriosisMesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsDisease Models, AnimalDisease ProgressionFemaleHumansRatsRats, WistarTumor Necrosis Factor-alphaVascular Endothelial Growth Factor ATumor Necrosis Factor-alphaVascular Endothelial Growth Factor ABiomarkersCytokinesDental pulpEndometriosisHistopathologyMesenchymal stem cells

Identifiers

PMID42218212
PMCPMC13458705

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.