Evidence map›Paper›PMID 42218197›Full record

ArticleScientific reports2026

Taguchi L9 optimization of BsPdaC-CD production in Escherichia coli.

Marc Carnicer, Pablo Haasnoot, Mònica Texidó, Antoni Planas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marc CarnicerLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain. marc.carnicer@iqs.url.edu.
Pablo HaasnootLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain.
Mònica TexidóLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain.
Antoni PlanasLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain. antoni.planas@iqs.url.edu.

Funding

HORIZON EUROPE Framework Programme 101209410MICINN, Spain PID2022-138252OB-I00
6 · The paper itself

Abstract

The production of sequence-defined partially acetylated chitooligosaccharides (paCOS) is a promising strategy for the valorization of chitin-rich waste into high-value bioactive compounds. The catalytic domain of a deacetylase from Bacillus subtilis (BsPdaC-CD), known to act on N-acetylglucosamine (GlcNAc) residues of chitooligosaccharides, represents a promising biocatalyst for paCOS production. In this work, a fed-batch process to produce the recombinant BsPdaC-CD in Escherichia coli BL21 was developed and optimized using a Taguchi L9 (3

Indexed as

AmidohydrolasesBacillus subtilisEscherichia coliBatch Cell Culture TechniquesBioreactorsCatalytic DomainChitinOligosaccharidesRecombinant ProteinsTemperatureAmidohydrolasesChitinchitin deacetylaseOligosaccharidesRecombinant ProteinsBioprocess optimizationChitinChitooligosaccharides (COS)Design of experimentsRecombinant protein productionTaguchi

Identifiers

PMID42218197
PMCPMC13458553

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.