Evidence map›Paper›PMID 42217158›Full record

ArticleJournal of Parkinson's disease2026

Declining verbal fluency after DBS in Parkinson's disease: Mental speed or executive dysfunction?

Vivianne H M Pennings, Esmée Verwijk, Rob M A de Bie, Rick Schuurman, Gert J Geurtsen

Abstract read
In one paragraph

Article in Journal of Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vivianne H M PenningsDepartment of Medical Psychology, Neuropsychology Section, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0009-0005-9626-125X
Esmée VerwijkDepartment of Medical Psychology, Neuropsychology Section, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.
Rob M A de BieAmsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.
Rick SchuurmanAmsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.
Gert J GeurtsenDepartment of Medical Psychology, Neuropsychology Section, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-2508-340X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundDespite the frequent decline in verbal fluency after STN-DBS surgery, the cause of decline remains unclear.ObjectiveThis study investigates whether mental speed and executive dysfunctions are underlying mechanisms of the phonemic verbal fluency decline after STN-DBS in Parkinson's patients.MethodsNeuropsychological assessments consisting of phonemic verbal fluency, Trail Making Test (TMT), and Stroop test were conducted before and 6 months after STN-DBS in 94 Parkinson's patients in the Galaxy Trial. A Reliable Change Index (RCI) pre- versus postoperative of verbal fluency was calculated, representing the magnitude of change. Content assessment of phonemic verbal fluency resulted in content profiles (clusters and switches).ResultsA statistically significant decline in postoperative phonemic verbal fluency was found, with statistically significant declined switching, while cluster size remained stable. Postoperative, statistically significant increases in time to perform TMT-B and all Stroop subtests was found. However, phonemic verbal fluency decline was correlated to change scores of Stroop I and II only. Comparisons of declined (

Indexed as

Deep Brain StimulationExecutive FunctionParkinson DiseaseSpeech DisordersAgedFemaleHumansMaleMiddle AgedNeuropsychological TestsProcessing SpeedStroop TestSubthalamic NucleusVerbal Behaviorcognitioncognitive aspectsdeep brain stimulationneuropsychological assessmentParkinson's diseaseverbal fluency

Identifiers

PMID42217158
PMCPMC13435166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.