Evidence map›Paper›PMID 42217108›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Cancer patient distress and health service use is linked with carer distress: evidence from a systematic review and meta-analysis.

Thi N T Huynh, Tracey DiSipio, Louisa G Collins, Lee Jones, Rachel E Neale, Vanessa L Beesley

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thi N T HuynhPsychedelic Medicine and Supportive Care Laboratory, QIMR Berghofer, Brisbane, Australia.
Tracey DiSipioPsychedelic Medicine and Supportive Care Laboratory, QIMR Berghofer, Brisbane, Australia.
Louisa G CollinsViertel Cancer Research Centre, Cancer Council Queensland, Brisbane, Australia.
Lee JonesStatistics Group, QIMR Berghofer, Brisbane, Australia.
Rachel E NealeSchool of Public Health, The University of Queensland, Brisbane, Australia.
Vanessa L BeesleyPsychedelic Medicine and Supportive Care Laboratory, QIMR Berghofer, Brisbane, Australia. v.beesley@uq.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFamily carers (caregivers) of cancer patients often have poor mental health, which may adversely affect patient wellbeing and health service use. We examined the evidence for this using a systematic review and meta-analyses.

methodsWe systematically searched online databases for studies reporting associations between carer psychological health and either: (a) psychological health of patients with cancer they cared for; or (b) health service use in carers or patients. Studies' risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Tool. We undertook meta-analyses to estimate pooled correlations for the most commonly reported associations between carer and patient psychological health. For associations between carer psychological health and carer and/or patient health service use, we conducted a narrative synthesis.

resultsOur search identified 11,911 records, 169 of which were eligible. The majority of studies were of high-to-moderate quality. Carers who were distressed, depressed, anxious, or had poor scores in the mental component of quality of life were significantly more likely to be caring for patients with these same outcomes (pooled effect sizes ranged from 0.28 to 0.42; all p < 0.001). Subgroup analyses by gender, disease stage, and study quality revealed no substantial differences. Carers with poor psychological health used general practice, mental healthcare, and hospital services more frequently than those who were psychologically healthy, and the patients they cared for used more medications and had more frequent emergency presentations.

conclusionThe inclusion of carers alongside patients in early psychosocial care may improve family outcomes and reduce health service use.

Indexed as

CaregiversHealth ServicesNeoplasmsStress, PsychologicalAnxietyHumansQuality of LifeAnxietyCancerCarers/caregiversDepressionDistressHealth service useMeta-analysisPsychological wellbeingSystematic review

Identifiers

PMID42217108
PMCPMC13222297

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.