Evidence map›Paper›PMID 42216971›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Clinical performance of [

Pierpaolo Alongi, Agostino Chiaravalloti, Simone Morea, Daniele Di Biagio

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pierpaolo Alongi *Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Piazza Marina 61, Palermo, 90139, Italy.
Agostino Chiaravalloti *Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, Rome, 00133, Italy. agostino.chiaravalloti@uniroma2.it.ORCID 0000-0002-8017-8858
Simone MoreaNuclear Medicine Centre, San Pietro Fatebenefratelli Hospital-Express Diagnostics, Via Cassia 600, Rome, 00189, Italy.
Daniele Di BiagioNuclear Medicine Centre, San Pietro Fatebenefratelli Hospital-Express Diagnostics, Via Cassia 600, Rome, 00189, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the clinical performance of [

methodsThis retrospective single-centre study included 103 consecutive patients with prostate cancer who underwent clinically indicated [

resultsOverall, PET was positive in 91/103 patients (88.3%), negative in 8/103 (7.8%), and indeterminate in 4/103 (3.9%). Positivity was observed in all patients scanned for primary staging (42/42, 100.0%) and in 49/61 patients (80.3%) referred for recurrence. The most frequent positive sites were primary lesion (57.3%), lymph nodes (35.0%), and bone (24.3%). In recurrence, PSA was significantly higher in PET-positive than in non-positive cases (median 2.40 vs. 0.42 ng/mL, p < 0.001). Log-transformed PSA was significantly associated with PET positivity (OR 7.40, 95% CI 2.18-25.11; p = 0.001), with an AUC of 0.912 (95% CI 0.828-0.974). PSA also correlated with the number of positive sites (rho = 0.620, p < 0.001).

conclusion[

Indexed as

Positron Emission Tomography Computed TomographyProstatic NeoplasmsAgedAged, 80 and overFluorine RadioisotopesHumansMaleMiddle AgedProstate-Specific AntigenRetrospective StudiesFluorine RadioisotopesProstate-Specific Antigen194-cm LAFOV PET/CTPiflufolastatProstate cancerPSAPSMA PET/CTTotal-body PET/CT

Identifiers

PMID42216971
PMCPMC13421277

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.