ArticleJACC. Case reports2026
Type II Kounis Syndrome Secondary to Amoxicillin Allergy.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Kounis Syndrome in the Modern Era: A Comprehensive Review of Allergic Acute Coronary Syndromes.Journal of clinical medicine · 2026Review
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKounis syndrome is an under-recognized cause of acute coronary syndrome precipitated by allergic or anaphylactic reactions. Recognition is critical, as management requires simultaneous treatment of both conditions. CASE SUMMARY: A 64-year-old woman with cardiovascular risk factors developed anaphylaxis after amoxicillin ingestion. Despite treatment with epinephrine and corticosteroids, she developed chest pain, with electrocardiogram showing inferior ST-segment elevations. Emergent catheterization revealed an occluded mid right coronary artery with nonobstructive left coronary disease. Successful percutaneous intervention was performed with drug-eluting stent placement, consistent with type II Kounis syndrome. DISCUSSION: This case represents 1 of approximately 3 reported cases in the literature of type II Kounis syndrome in a female patient secondary to amoxicillin, highlighting the importance of cardiac vigilance during anaphylaxis management. TAKE-HOME MESSAGES: Kounis syndrome should be suspected when chest pain develops during anaphylaxis, prompting urgent electrocardiographic evaluation. Management requires balancing conflicting therapies for anaphylaxis and acute coronary syndrome.
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