Evidence map›Paper›PMID 42216932›Full record

ArticleJACC. Asia2026

7-Year Outcomes of Balloon-Expandable Versus Self-Expanding Valves in Women Undergoing Transcatheter Aortic Valve Replacement.

Juri Iwata, Masanori Yamamoto, Kei Kamata, Ryo Arita, Tomonari Moriizumi, Toshinobu Ryuzaki, Hikaru Tsuruta, Takahiro Tokuda, Shinichi Shirai, Yusuke Watanabe and 18 more

Abstract read
In one paragraph

Article in JACC. Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Juri IwataDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Masanori YamamotoDepartment of Cardiology, Toyohashi Heart Center, Toyohashi, Japan; Department of Cardiology, Nagoya Heart Center, Nagoya, Japan; Department of Cardiology, Gifu Heart Center, Gifu, Japan.
Kei KamataDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Ryo AritaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Tomonari MoriizumiDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Toshinobu RyuzakiDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Hikaru TsurutaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Takahiro TokudaDepartment of Cardiology, Nagoya Heart Center, Nagoya, Japan.
Shinichi ShiraiDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Yusuke WatanabeDepartment of Cardiology, Teikyo University, Tokyo, Japan.
Toru NaganumaDepartment of Cardiology, New Tokyo Hospital, Chiba, Japan.
Futoshi YamanakaDepartment of Cardiology, Shonan Kamakura General Hospital, Kanagawa, Japan.
Masahiko NoguchiDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.
Yohei OhnoDepartment of Cardiology, Tokai University, Isehara, Japan.
Masaki IzumoDepartment of Cardiology, St. Marianna University School of Medicine, Kawasaki, Japan.
Hidetaka NishinaDepartment of Cardiology, Tsukuba Medical Center Hospital, Tsukuba, Japan.
Masahiko AsamiDivision of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.
Gaku NakazawaDepartment of Cardiology, Kinki University, Osaka, Japan.
Fumiaki YashimaDepartment of Cardiology, Saiseikai Utsunomiya Hospital, Utsunomiya, Japan.
Hirofumi HiokiDepartment of Cardiology, IMS Tokyo Katsushika General Hospital, Tokyo, Japan.
Tetsuro ShimuraDepartment of Cardiology, Gifu Heart Center, Gifu, Japan.
Kenichi IshizuDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Yasushi FukuDepartment of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan.
Toshiaki OtsukaDepartment of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan.
Hideyuki ShimizuDepartment of Cardiovascular Surgery, Keio University School of Medicine, Tokyo, Japan.
Masaki IedaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Kentaro HayashidaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan. Electronic address: khayashidamd@gmail.com.
OCEAN-TAVI Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFemale patients with aortic stenosis frequently present with a small aortic annulus (SAA), which may result in unfavorable echocardiographic cardiac function after transcatheter aortic valve replacement. However, evidence comparing the long-term outcomes of balloon-expandable valves (BEVs) and self-expanding valves (SEVs) in this context is limited.

objectivesThis study compares the 7-year clinical outcomes after transcatheter aortic valve replacement using BEV and SEV in female patients.

methodsOverall, 1,827 female patients treated with BEV and 805 treated with SEV were identified from the Optimized transCathEter vAlvular intervention-Transcatheter Aortic Valve Implantation (OCEAN-TAVI) registry. One-to-one propensity score matching (PSM) was performed to adjust for confounding factors, resulting in 744 matched patients per group. The primary clinical endpoints included all-cause mortality, stroke, and heart failure rehospitalization.

resultsOverall, 1,303 patients (87.6%) had a SAA. Echocardiographic assessments indicated that BEV had smaller effective orifice area and higher mean pressure gradient than did SEV throughout the follow-up period. In the PSM analysis, BEV was associated with lower all-cause mortality (51.5% vs 57.4%; log-rank, P = 0.021) and stroke at 7 years (10.8% vs 16.7%; Fine-Gray, P = 0.008). Heart failure rehospitalization rates were similar between groups. In multivariable analyses, valve type was not independently associated with long-term outcomes, and subgroup analyses considering annulus size yielded consistent results.

conclusionsFor women predominantly presenting with a SAA, BEV demonstrated decreased echocardiac performance compared with SEV. Although PSM analysis indicated more favorable outcomes with BEV, valve type was not independently associated with long-term prognosis after multivariable adjustment. These findings suggest that both types of transcatheter heart valves may be an acceptable option in this patient population.

Indexed as

balloon-expandable valvesself-expanding valvessmall aortic annulustranscatheter aortic valve replacementwomen

Identifiers

PMID42216932
PMCPMC13458811

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.