Evidence map›Paper›PMID 42216566›Full record

ReviewThe Journal of clinical endocrinology and metabolism2026

Approach to the patient: investigation of postmenopausal androgen excess.

Lauren Madden-Doyle, Kevin Bowers, Mark Sherlock, Michael W O'Reilly

Abstract readReview
In one paragraph

Review in The Journal of clinical endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren Madden-DoyleAndrogens in Health and Disease Research Group, Academic Division of Endocrinology, Department of Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin 9, Republic of Ireland.
Kevin BowersAndrogens in Health and Disease Research Group, Academic Division of Endocrinology, Department of Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin 9, Republic of Ireland.
Mark SherlockAndrogens in Health and Disease Research Group, Academic Division of Endocrinology, Department of Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin 9, Republic of Ireland.
Michael W O'ReillyAndrogens in Health and Disease Research Group, Academic Division of Endocrinology, Department of Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin 9, Republic of Ireland.ORCID 0000-0002-9108-9105

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgen excess in postmenopausal women presents a challenging clinical conundrum. A crucial component in management involves identification of the underlying etiology with a focus on detection of potentially malignant pathology or underlying genetic syndromes. A basic understanding of androgen physiology in women and the associated alterations during the menopausal transition is required to accurately risk stratify this cohort and streamline investigations. Over the course of this article, we will propose an approach to investigation and management of postmenopausal androgen excess that focuses on clinical, biochemical, and radiological cues. Additionally, we will suggest an algorithmic approach to clinical and biochemical diagnostics that is underpinned by identification of red flag features of the underlying pathology.

Indexed as

AndrogensHyperandrogenismPostmenopauseFemaleHumansOvarian NeoplasmsAndrogensadrenocortical carcinomaandrogen excessmenopauseovarian hyperthecosisvirilizing ovarian tumor

Identifiers

PMID42216566
PMCPMC13466947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.