Evidence map›Paper›PMID 42216453›Full record

SynthesisHuman vaccines & immunotherapeutics2026

Strategies implemented to increase HPV vaccine uptake and confidence among men who have sex with men and transgender people: A systematic review.

Helena Avermark, Sofia Tzirita, Erik Radix, Sunjuri Sun, Sibylle Herzig van Wees

Abstract readSystematic Review
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Helena AvermarkDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0009-0008-8429-1744
Sofia TziritaDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Erik RadixRFSL Ungdom, Stockholm, Sweden.
Sunjuri SunDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Sibylle Herzig van WeesDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Men who have sex with men (MSM) and transgender persons are disproportionately affected by HPV-related disease. The HPV vaccine effectively prevents infection, but vaccine uptake remains suboptimal in this group. Thus, this systematic review aimed to synthesize the literature on interventions and strategies implemented to increase HPV vaccine confidence and uptake among MSM and transgender persons. Six databases were searched in May 2025. We assessed risk of bias and extracted and descriptively summarized key data through narrative synthesis and content analysis. Sixteen articles reporting on eight interventions were identified, all implemented in high-income settings. The interventions can be broadly categorized into two types: strategies to integrate HPV vaccination into existing health services and digital interventions aimed at generating vaccine demand. Overall, evidence remains limited on interventions to increase HPV vaccine uptake in these groups, particularly studies focusing on the needs of transgender persons.

Indexed as

Homosexuality, MalePapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CareTransgender PersonsVaccinationFemaleHuman Papillomavirus VirusesHumansMalePapillomavirus VaccinesHPV vaccinationHuman papillomavirusinterventionsmen who have sex with mensystematic reviewtransgender persons

Identifiers

PMID42216453
PMCPMC13224759

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.