Evidence map›Paper›PMID 42216091›Full record

ArticleInternational journal of retina and vitreous2026

Rhegmatogenous and tractional retinal detachment in eyes with retinoblastoma: a retrospective surgical case series from a tertiary eye center.

Hend AlSafran, Marcos J Rubio Caso, Gorka Sesma, Adhwa Alsadoon, Abdullah M Khan, Saleh AlMesfer

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Article in International journal of retina and vitreous, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hend AlSafran *Vitreoretinal Division, King Khaled Eye Specialist Hospital & Research Center, Riyadh, Saudi Arabia.ORCID http://orcid.org/0009-0007-1308-9883
Marcos J Rubio CasoVitreoretinal Division, King Khaled Eye Specialist Hospital & Research Center, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0002-7072-9855
Gorka Sesma *Pediatric Ophthalmology & Strabismus Division, King Khaled Eye Specialist Hospital & Research Center, West Building, 2nd Floor, Riyadh, 12329, Saudi Arabia. gsesma@kkesh.med.sa.ORCID http://orcid.org/0000-0002-4320-448X
Adhwa AlsadoonVitreoretinal Division, King Khaled Eye Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Abdullah M KhanPediatric Ophthalmology & Strabismus Division, King Khaled Eye Specialist Hospital & Research Center, West Building, 2nd Floor, Riyadh, 12329, Saudi Arabia.ORCID http://orcid.org/0000-0003-1125-7891
Saleh AlMesferPediatric Ophthalmology & Strabismus Division, King Khaled Eye Specialist Hospital & Research Center, West Building, 2nd Floor, Riyadh, 12329, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the clinical characteristics, management strategies, and surgical outcomes of tractional and/or rhegmatogenous retinal detachment (TRD/RRD) in eyes with retinoblastoma (RB).

methodsA retrospective surgical case series of patients with treated RB at a tertiary referral center (June 2014-April 2025) who developed non-exudative retinal detachment (RD) was conducted. The data included demographics, tumor activity, RB treatment modalities received, RD features, surgical approach, complications, anatomical reattachment, and final visual acuity.

resultsSeven eyes of seven patients (0.9%) developed TRD or RRD. Four eyes had RRD, two had combined RRD/TRD, and one had TRD. Early RRD during active RB was treated with nondrainage scleral buckling (n = 2), whereas late detachments after complete tumor regression underwent pars plana vitrectomy with silicone oil tamponade (n = 4). Anatomical reattachment at one year was achieved in 83.3% of the operated eyes (five of six eyes undergoing surgery), with no cases of tumor seeding or reactivation observed. One eye was enucleated due to tumor progression. Visual acuity improved to baseline or better in 71.4% of the eyes.

conclusionsIn this small series, early RRD during active RB was managed with nonsurgical scleral buckling without evidence of tumor dissemination, and late complex RRD after confirmed tumor quiescence was treated with pars plana vitrectomy and silicone oil tamponade with favorable anatomical outcomes. No tumor seeding or reactivation was observed in any case. However, these findings should be interpreted with caution, given the small sample size, and do not allow definitive conclusions regarding oncologic safety.

Indexed as

RetinoblastomaRhegmatogenous retinal detachmentSurgical outcomesTractional retinal detachmentVitreoretinal surgery

Identifiers

PMID42216091
PMCPMC13430755

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.