ArticleTropical medicine and health2026
Clinical outcomes and plasmid-associated features in KPC-producing Klebsiella pneumoniae bacteraemia.
Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe genetic epidemiology of carbapenem-resistant Klebsiella pneumoniae (CRKP) is geographically distinct. This study aimed to investigate the association of capsular types and plasmid-mediated factors with mortality in patients with CRKP bacteraemia.
methodsPatients with CRKP bacteraemia were enrolled at two medical centres between 2017 and 2021. Capsular typing, antimicrobial susceptibility testing, polymerase chain reaction (PCR) for carbapenemase-encoding genes in all strains, and whole-genome sequencing (WGS) of selected strains were performed.
resultsAmong 402 patients with monomicrobial CRKP bacteraemia, 238 (59.2%) strains were carbapenemase-producing. Of the K47 strains (n = 188), 89.9% carried bla
conclusionsCapsular types and the structural characteristics of bla
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