ReviewBMC infectious diseases2026
A successful individualized comprehensive therapy for carbapenem-resistant Klebsiella pneumoniae induced multifocal brain abscesses: a case report and literature review.
Review in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbapenem-resistant Klebsiella pneumoniae (CRKP)-induced brain abscess is an exceedingly rare disease. We presented the fourth case of CRKP-induced brain abscess but the first multifocal and most complicated one accompanied by intracranial Epstein-Barr virus detection positive. The patient was treated with a regime of intravenous ceftazidime/avibactam combined with intrathecal colistimethate sodium. To our knowledge, this represented the first reported application of such a regimen for a CRKP-induced brain abscess. When the abscess formed an intact envelope, the patient underwent craniotomy for resection. Postoperatively, the antibiotic regimen was continued for 2 weeks until the CSF examination became nearly normal. The patient remained asymptomatic over the next 12 months follow-up without recurrences. This case highlights the rarity of CRKP-induced brain abscess and provides a novel combination of antibiotic regimen, which also emphasizes the necessity for individualized and comprehensive therapeutic strategy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.