ArticleBMC cardiovascular disorders2026
Association of alkaline phosphatase to platelet ratio index with ICU mortality in patients with cardiac arrest.
Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
BACKGROUND AND
objectivesThe present study aimed to investigate the association between the alkaline phosphatase-to-platelet ratio index (APPRI) and intensive care unit (ICU) mortality in patients with cardiac arrest (CA), and further explore its potential value for risk stratification in this specific population.
methodsA total of 374 CA patients were included in our analysis. They were divided into the survivor group (n = 180) and non-survivor group (n = 194) based on ICU survival status. Baseline characteristics of the two groups were summarized and compared. Univariate and multivariate logistic regression analyses were conducted to explore the association between the alkaline APPRI and ICU mortality. Receiver operating characteristic (ROC) curve analysis was used to determine APPRI's optimal cutoff value for predicting ICU mortality. The Kaplan-Meier method was applied to estimate survival curves of different groups, with the log-rank test used to compare survival differences.
resultsThe non-survivor group exhibited higher APPRI values than the survivor group (0.430 [0.296, 0.733] vs.0.358 [0.246, 0.533)], P < 0.001). Univariate logistic regression analysis showed that APPRI (odds ratio (OR) = 1.077, 95% confidence interval (CI): 1.013-1.146, P = 0.018) was associated with ICU mortality. Multivariate logistic regression analysis revealed that APPRI was one of the independent predictors of ICU mortality (OR = 1.110, 95% CI: 1.022-1.205, P = 0.013). The ROC curve determined the APPRI optimal cut-off value for ICU mortality to be 0.576. The Kaplan-Meier curves showed that patients with APPRI > 0.576 had a higher ICU mortality than that of patients with APPRI ≤ 0.576 (log-rank test P = 0.017).
conclusionsAPPRI is independently associated with ICU mortality in patients with CA, and the index effectively stratifies CA patients at risk of ICU deat.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.