Evidence map›Paper›PMID 42215815›Full record

ArticleAnalytical and bioanalytical chemistry2026

Trypsin-, proteinase K-, and ribonuclease T1-functionalized magnetic nanoparticle-immobilized enzyme reactors based on polyelectrolyte multilayer platform for biopharmaceutical analysis.

Yachao Hao, Niklas Carstensen, Ronny Loeffler, Benjamin Junker-Reiss, Dominique Lunter, Michael Lämmerhofer

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yachao HaoInstitute of Pharmaceutical Sciences, Pharmaceutical (Bio-)Analysis, University of Tübingen, Auf Der Morgenstelle 8, 72076, Tübingen, Germany.
Niklas CarstensenInstitute of Pharmaceutical Sciences, Pharmaceutical (Bio-)Analysis, University of Tübingen, Auf Der Morgenstelle 8, 72076, Tübingen, Germany.
Ronny LoefflerCenter for Light-Matter Interaction, Sensors & Analytics (LISA+), University of Tübingen, Auf Der Morgenstelle 15, 72076, Tübingen, Germany.
Benjamin Junker-ReissCenter for Light-Matter Interaction, Sensors & Analytics (LISA+), University of Tübingen, Auf Der Morgenstelle 15, 72076, Tübingen, Germany.ORCID http://orcid.org/0000-0002-2229-0534
Dominique LunterInstitute of Pharmaceutical Sciences, Pharmaceutical (Bio-)Analysis, University of Tübingen, Auf Der Morgenstelle 8, 72076, Tübingen, Germany.ORCID http://orcid.org/0000-0003-3984-4035
Michael LämmerhoferInstitute of Pharmaceutical Sciences, Pharmaceutical (Bio-)Analysis, University of Tübingen, Auf Der Morgenstelle 8, 72076, Tübingen, Germany. michael.laemmerhofer@uni-tuebingen.de.ORCID http://orcid.org/0000-0002-1318-0974

Funding

Chinese Government Scholarship 202308210135Deutsche Forschungsgemeinschaft INST 37/1318-1 FUGGDeutsche Forschungsgemeinschaft INST 37/821-1 FUGG
6 · The paper itself

Abstract

Immobilized enzyme reactors (IMERs) have gained increasing attention owing to their numerous advantages, including reusability, easy handling, cost saving, and prolonged lifetime. In this work, Fe

Indexed as

Biopharmaceutical analyticsImmobilized enzyme reactorMagnetic nanoparticleProteaseRibonucleaseSample preparation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.