Evidence map›Paper›PMID 42215759›Full record

ArticleJournal of fluorescence2026

Synthesis and Characterization of Conformationally Restricted Monocyclic Cyanine Dyes.

Haichuang Lan, Bin Yang, Huayang Liang, Peng Geng, Dan Luo, Shuzhang Xiao

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haichuang LanCollege of Materials and Chemical Engineering, China Three Gorges University, Yichang, 443002, Hubei, China.
Bin YangCollege of Materials and Chemical Engineering, China Three Gorges University, Yichang, 443002, Hubei, China.
Huayang LiangCollege of Materials and Chemical Engineering, China Three Gorges University, Yichang, 443002, Hubei, China.
Peng GengCollege of Materials and Chemical Engineering, China Three Gorges University, Yichang, 443002, Hubei, China. gengpeng@ctgu.edu.cn.
Dan LuoCollege of Materials and Chemical Engineering, China Three Gorges University, Yichang, 443002, Hubei, China.
Shuzhang XiaoCollege of Materials and Chemical Engineering, China Three Gorges University, Yichang, 443002, Hubei, China. shuzhangxiao@ctgu.edu.cn.

Funding

111 Project of China D20015China Three Gorges University 1910103Department of Education of Hubei Province D20211202National Natural Science Foundation of China 22171163
6 · The paper itself

Abstract

Cyanine dyes are widely used fluorescent probes in bioimaging, yet conventional linear cyanine suffer from low fluorescence quantum yield, small Stokes shifts, poor photostability and chemical stability, due to rotational relaxation of the polymethine chain. In this work, we report the design, synthesis, and characterization of cyclic monocyanine dyes, in which the methine bridge is cyclized to form a rigidified, partially asymmetric framework. This conformational restriction suppresses non-radiative decay pathways and reduces aggregation to give high fluorescence quantum yield (~ 5%) both in dilute solution and in the solid state. Meanwhile, symmetry breaking enhances Stokes shifts and minimizes self-absorption, highlighting its suitability for bioimaging.

Indexed as

BioimagingCyclic structureHigh quantum yieldLarge Stokes shiftMonocyanine

Identifiers

PMID42215759

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.