Evidence map›Paper›PMID 42215758›Full record

ArticleJournal of fluorescence2026

A Galactose-Modified Light-Activatable Persulfurated Arene Fluorescent Probe for Targeted Imaging of Polarity and Viscosity in Liver Cancer Cells.

Pan-Xin Ge, Yan Rong, Lu-Lu Sun, Yuqing Hu, Xianzhi Chai, Hai-Hao Han, Liangliang Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pan-Xin GeSchool of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China.
Yan RongSchool of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212100, China.
Lu-Lu SunShandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, 264117, China.
Yuqing HuSchool of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212100, China.
Xianzhi ChaiSchool of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212100, China. chaixianzhi@163.com.
Hai-Hao HanSchool of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China. hanhaihao@simm.ac.cn.
Liangliang ZhuState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200438, China.

Funding

Key R&D Program of Shandong Province, China 2025CXPT012National Natural Science Foundation of China 22308134National Natural Science Foundation of China 22377135Natural Science Foundation of Jiangsu Province BK20220644Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX25_4390 and SJCX25_2540Shandong Laboratory Program SYS202205Taishan Scholars Program tsqn202312305the Fundamental Research Projects of Science & Technology Innovation and development Plan in Yantai City 2023JCYJ059
6 · The paper itself

Abstract

Monitoring intracellular physiological changes, particularly the dysregulation of key microenvironmental parameters like viscosity and polarity, provides critical functional insights into diseased states. Herein, we report a fluorescent probe, HTB-βGal, based on persulfurated arenes and sensitive to both polarity and viscosity. Modified with galactose, the probe exhibits good water solubility and is initially non-emissive in aqueous solution. Upon light irradiation, its fluorescence gradually increases due to the photoexcitation-induced aggregation (PEIA) characteristic of the persulfurated arene core. In the H

Indexed as

Fluorescent DyesGalactoseLightLiver NeoplasmsOptical ImagingFluorescent Chemosensor CompoundsHumansViscosityFluorescent Chemosensor CompoundsFluorescent DyesGalactoseFluorescent probesLiver cancerPhotoexcitation-induced aggregationPolarityViscosity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.