Evidence map›Paper›PMID 42215712›Full record

ArticleMikrochimica acta2026

Development of a covalent organic framework/graphene oxide aptasensor for electrochemical penicillin detection.

Zhenglin Lu, Meixin Huang, Xinxin Liu, Zhipeng Liang, Ziao Zong, Feng Guo, Xiang Chen

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhenglin LuKey Laboratory of Biomedical Material Research of Guangxi (Cultivation), Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, P. R. China.
Meixin HuangKey Laboratory of Biomedical Material Research of Guangxi (Cultivation), Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, P. R. China.
Xinxin LiuThe Affiliated Liuzhou Hospital of Youjiang Medical University for Nationalities, Liuzhou, Guangxi, 545007, P. R. China.
Zhipeng LiangSchool of Medical Technology and Artificial Intelligence, Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, P. R. China.
Ziao ZongSchool of Medical Technology and Artificial Intelligence, Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, P. R. China.
Feng GuoSchool of Medical Technology and Artificial Intelligence, Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, P. R. China. guofeng1510@yeah.net.
Xiang ChenThe Affiliated Liuzhou Hospital of Youjiang Medical University for Nationalities, Liuzhou, Guangxi, 545007, P. R. China. Chenxiang_1984@126.com.

Funding

Guangxi Natural Science Foundation 2025GXNSFHA069134Youjiang Medical University for Nationalities RZ2200002225
6 · The paper itself

Abstract

The rapid and sensitive detection of trace antibiotics in environmental and biological samples is crucial for food safety and public health. This study presents a novel electrochemical aptasensor based on a porous covalent organic frameworks/graphene oxide (namely COF/GO) hybrid material for selectively detecting penicillin (PCL). A specific aptamer was immobilized on the modified electrode surface for high-affinity recognition of PCL. The binding event between the aptamer and PCL induces a measurable change in the electrochemical signal, which is quantitatively analyzed using differential pulse voltammetry (DPV). The developed aptasensor demonstrated excellent performance with a wide linear range from 0.01 ng mL

Indexed as

Anti-Bacterial AgentsAptamers, NucleotideBiosensing TechniquesElectrochemical TechniquesGraphiteMetal-Organic FrameworksPenicillinsElectrodesLimit of DetectionAnti-Bacterial AgentsAptamers, Nucleotidegraphene oxideGraphiteMetal-Organic FrameworksPenicillinsCovalent organic frameworksDifferential pulse voltammetryElectrochemical aptasensor; Modified glassy carbon electrodeGraphene oxidePenicillin

Identifiers

PMID42215712

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.