Evidence map›Paper›PMID 42215682›Full record

ArticleCommunications biology2026

Copper ions restore antibacterial activity of tigecycline by regulating photodegradation pathway under light exposure‌.

Jinjing Xue, Qianyu Zhou, Yuanyuan Liu, Lin Ma, Yonglin Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinjing Xue *Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, School of Life Sciences, Ningxia University, Yinchuan, China.
Qianyu Zhou *State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.
Yuanyuan LiuKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, School of Life Sciences, Ningxia University, Yinchuan, China.
Lin MaKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, School of Life Sciences, Ningxia University, Yinchuan, China.
Yonglin ZhouKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, School of Life Sciences, Ningxia University, Yinchuan, China. zhouyonglin333@nxu.edu.cn.ORCID http://orcid.org/0000-0001-7704-187X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodegradation of tetracyclines is a research hotspot due to deactivation and toxic degradation products. We observed that only tigecycline and minocycline, at working concentrations, exhibit a reduction in antibacterial activity under light exposure. In contrast, other tetracyclines maintain antibacterial activity post-degradation. Here we have successfully identified chalcanthite, from the mineral drug resource library. Cu

Indexed as

Anti-Bacterial AgentsCopperLightPhotolysisTigecyclineAnimalsMicrobial Sensitivity TestsAnti-Bacterial AgentsCopperTigecycline

Identifiers

PMID42215682
PMCPMC13507280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.