Evidence map›Paper›PMID 42215624›Full record

Trial reportScientific reports2026

Effectiveness of a home-based physical exercise intervention in patients with hip fragility fractures: a randomized controlled trial.

Rocío Segura-Ruiz, Macarena Ruiz-Cañete, Adoración Muñoz-Alonso, Rafael Jiménez-Esquinas, Estíbaliz Moreno-González, Mª Pilar Serrano-Lázaro, Pedro José Armenteros-Ortiz, Claudia Rivas-Cruces, Giovanni Piva, Nicola Lamberti and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04934358 (Effectiveness of a Follow-up Program Based on Motivational Interventions and Physical Exercise in Patients With Fragility Fracture), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04934358 naunknown statusnot on this map

Effectiveness of a Follow-up Program Based on Motivational Interventions and Physical Exercise in Patients With Fragility Fracture: Randomized Controlled Clinical Trial.

TypeinterventionalSponsorMaimónides Biomedical Research Institute of CórdobaRan2022 to 2024Enrolled100ConditionsFragility FractureArmsPhysical and motivational follow-up treatment, Usual care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rocío Segura-Ruiz *GC31 Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Macarena Ruiz-Cañete *GC31 Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Adoración Muñoz-AlonsoGC31 Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Rafael Jiménez-EsquinasDepartment of Nursing, Pharmacology and Physiotherapy, University of Córdoba, Av. Menéndez Pidal, s/n, Poniente Sur, Córdoba, 14004, Spain.
Estíbaliz Moreno-GonzálezHospital Universitario Reina Sofía, Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Mª Pilar Serrano-LázaroHospital Universitario Reina Sofía, Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Pedro José Armenteros-OrtizHospital Universitario Reina Sofía, Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Claudia Rivas-CrucesGC31 Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain.
Giovanni PivaDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via Luigi Borsari 46, Ferrara, 44121, Italy.
Nicola LambertiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via Luigi Borsari 46, Ferrara, 44121, Italy. nicola.lamberti@unife.it.
Fabio ManfrediniDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via Luigi Borsari 46, Ferrara, 44121, Italy.
Pablo Jesús López-SotoGC31 Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal, s/n, Poniente Sur, 14004, Córdoba, Spain. pablo.lopez@imibic.org.

Funding

Ministry of Health, Government of Andalusia PIGE-0040-2020
6 · The paper itself

Abstract

We aimed to test the effectiveness of an invidually tailored home-based exercise intervention compared with usual care for independence, functional capacity and quality of life in patients with hip fragility fractures. In this single-blinded randomized-controlled trial (NCT04934358), patients with surgically treated fragility hip fractures were randomized to receive a 3-month exercise intervention or usual care. The exercise group performed a predetermined number of steps per day with resting pauses and a number of sit-to-stand exercises at home. The outcomes collected at baseline, at the end of the program and at follow up (6-months) included: the Barthel Index (primary outcome), quality of life, cognition and depression levels, 6-minute walking test, and 5-time sit-to-stand test. A total of 35 patients were randomized: 16 to the exercise group and 19 to the control group (mean age 80 ± 10 years, men n = 9). At the end of the program, patients in the exercise group presented significantly greater improvement in all primary and secondary outcomes than those in the control group did (Barthel Index variations: 12 ± 4 vs. 7 ± 5; p = 0.046), although both groups exhibited significant improvements from baseline for almost all the outcomes. Compared with usual care, a simple, individually tailored home-based exercise program favored the recovery of independence, quality of life, and functional capacity after hip fragility fractures.

Indexed as

Exercise TherapyHip FracturesAgedAged, 80 and overFemaleHome Care ServicesHumansMaleProximal Femoral FracturesQuality of LifeSingle-Blind MethodTreatment OutcomeExerciseFrailty fracturesFunctional independenceHip fractureHome-based therapyRehabilitation

Identifiers

PMID42215624
PMCPMC13454571

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.