Evidence map›Paper›PMID 42215610›Full record

Trial reportScientific reports2026

Effect of foot orthotics on running kinetics in adults with anterior cruciate ligament reconstruction: A controlled laboratory study.

Ebrahim Piri, AmirAli Jafarnezhadgero, Mahrokh Dehghani, Heidar Sajedi, Valdeci Carlos Dionisio

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ebrahim PiriDepartment of Sports Biomechanics, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
AmirAli JafarnezhadgeroDepartment of Sports Biomechanics, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran. amiralijafarnezhad@gmail.com.ORCID http://orcid.org/0000-0002-2739-4340
Mahrokh DehghaniDepartment of Sports Biomechanics, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
Heidar SajediSport Science Faculty, Department of Movement and Training Sciences, Düzce University, Düzce, Turkey.
Valdeci Carlos DionisioFaculty of Physical Education and Physiotherapy, Federal University of Uberlandia, Uberlandia, MG, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with anterior cruciate ligament reconstruction and pronated feet (ACLR-PF) often display abnormal running ground reaction forces (GRFs), which are associated with higher re-injury risk and post-traumatic osteoarthritis. While foot orthoses (FOs) are used to influence biomechanics, their effectiveness at various post-operative stages in this group remains unknown. This study aimed to evaluate the immediate impact of different FOs on GRFs during running in males with ACLR-PF at 6-, 12-, and 18-months post-operative, compared to a healthy control group. This controlled laboratory study with randomized repeated orthotic conditions included males with ACLR-PF at 6, 12, and 18-months post‑operative, as well as healthy controls. Forty-five right-footed males with ACLR-PF were divided into three groups based on post-operative duration: 6 ± 1 months (group A, n = 15), 12 ± 1 months (group B, n = 15), and 18 ± 1 months (group C, n = 15). A matched health control group (group D, n = 15) was also included. Participants ran at 3.2 m/s under four randomized footwear conditions: control shoe, placebo orthotic, double-density orthotic, and arch-support orthotic. Three-dimensional GRFs were collected using a force plate. ACLR-PF groups at 12- and 18-months showed significantly higher impact vertical peaks and vertical loading rates than the healthy group. The 6-months ACLR-PF group had a longer time-to-peak for the impact vertical peak. Peak positive free moment was higher in the 6- and 18-months ACLR-PF groups compared to controls. A significant main effect of FOs was detected, with the double-density orthotic significantly decreasing the peak positive free moment relative to the control shoe. Significant group-by-FOs interactions indicated that the impact of specific orthoses on peak posterior force, loading rate, and stance time depended on the post-operative stage. Abnormal loading patterns continue up to 18-months after ACLR in individuals with PF, highlighting a critical window for intervention. FOs, especially double-density designs, can immediately adjust specific maladaptive GRFs, such as lowering excessive rotational moments. An orthotic prescription should be customized to the individual's specific biomechanical deficits and the stage in the rehabilitation process. In this controlled laboratory study, double-density and arch-support FOs acutely modified selected GRFs in males with ACLR and PF across post-operative stages. These findings suggest that FOs may provide immediate biomechanical adjustments during running; however, the long‑term clinical relevance of these acute changes remains uncertain and requires longitudinal investigation.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionFoot OrthosesRunningAdultBiomechanical PhenomenaHumansKineticsMaleYoung AdultAnterior cruciate ligament surgeryFlat FeetGait analysisInsolesKinetic

Identifiers

PMID42215610
PMCPMC13454134

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.