Evidence map›Paper›PMID 42214408›Full record

ArticlePhysics in medicine and biology2026

Experimental validation of Davis LUT module with photonic crystals for GATE simulations.

Xuzhi He, Nicolaus Kratochwil, Gerard Ariño-Estrada, Vinay Jain, Emilie Roncali

Abstract readValidation Study
In one paragraph

Article in Physics in medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuzhi HeDepartment of Biomedical Engineering, University of California at Davis, Davis, CA 95616, United States of America.ORCID 0000-0002-4082-8166
Nicolaus KratochwilDepartment of Biomedical Engineering, University of California at Davis, Davis, CA 95616, United States of America.ORCID 0000-0001-5297-1878
Gerard Ariño-EstradaDepartment of Biomedical Engineering, University of California at Davis, Davis, CA 95616, United States of America.ORCID 0000-0002-6411-191X
Vinay JainDepartment of Biomedical Engineering, University of California at Davis, Davis, CA 95616, United States of America.ORCID 0009-0007-5660-6481
Emilie RoncaliDepartment of Biomedical Engineering, University of California at Davis, Davis, CA 95616, United States of America.ORCID 0000-0002-2439-1064

Funding

AI-accelerated optical simulation for fast timing nuclear imagingR01EB034475 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Emilie Roncali · 2023 to 2026
$2.4M
NIBIB NIH HHS R01 EB034475
6 · The paper itself

Abstract

Positron emission tomography (PET) image quality is partially determined by PET detector performance, which can be improved by increasing the optical photon harvest from scintillator to photodetector. Due to the steep index mismatch at this interface, the optical photon critical angle limits the harvest. Photonic crystals (PhCs) are periodic nanostructures that can break through the critical angle limit, with a size comparable to the optical photon wavelength. Previous work including both simulation and experimental studies indicated that PhCs can enhance PET detectors' optical photons harvest. However, computational models can be inaccurate due to the necessity of using wave optics modeling, which can be challenging when modeling fabricated PhCs due to physical defects (e.g. loss of periodicity). Our group has developed a new computational method based on the previous look-up-table (LUT) Davis model implemented in the Monte Carlo simulation software GATE. The novel method models fabricated PhCs, including defects: first, we used laser characterization to analyze non-ideal PhCs and then used a reverse design approach to find the actual geometry of these 'Effective PhCs' LUT. We built the 'Effective PhCs' LUT and incorporated it into GATE. The new model was tested with 3 × 3 × 20 mm

Indexed as

Monte Carlo MethodPhotonsPositron-Emission Tomographydetectorinverse designopticsphotonic crystalspositron emission tomography

Identifiers

PMID42214408
PMCPMC13270158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.