ArticleJournal of the mechanical behavior of biomedical materials2026
Hypertension drives thoracic aortic aneurysm and dissection in male, but not female, Marfan mice.
Article in Journal of the mechanical behavior of biomedical materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hypertension is regarded clinically to be a primary risk factor for thoracic aortic disease, yet few studies have examined roles of sustained elevations in blood pressure in mouse models that are genetically predisposed to aortopathy. We quantified and compared effects of chronic blood pressure elevation, achieved using a high salt diet plus induced endothelial dysfunction, on the ascending aorta in age- and sex-matched adult wild-type and Fbn1
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