Evidence map›Paper›PMID 42213831›Full record

ArticleScience advances2026

Xinrui Shi, Loryn Blackburn, Sandeep Singh, Martyna Glowczyk-Gluc, Anam Tajammal, Shafaque Zahra, Shailesh Kumar, Robert Cornelison, Chen Liang, Fujun Qin and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xinrui ShiDepartment of Biochemistry and Molecular Biology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0009-0003-1739-8895
Loryn BlackburnDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-2001-873X
Sandeep SinghDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Martyna Glowczyk-GlucDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0009-0006-2222-0604
Anam TajammalDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Shafaque ZahraDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-3697-8065
Shailesh KumarDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-1872-9903
Robert CornelisonDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Chen LiangDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Fujun QinDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0003-2337-7137
Aiqun LiuDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Shitong LinDepartment of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Yue TangSchool of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Justin ElfmanDepartment of Biochemistry and Molecular Biology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Thomas ManleyDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0009-0002-3040-7496
Timothy BullockDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0001-6141-3261
Doris M HaverstickDepartment of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Peng WuDepartment of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.ORCID 0000-0003-4498-7663
Hui LiDepartment of Biochemistry and Molecular Biology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-7879-1792

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Dina Gould Halme · 1987 to 2026
$72.1M
Novel mechanisms in DNA mismatch repairR01GM132128 · NIGMS · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI KADYROV, FARID · 2020 to 2023
$1.2M
Cytek Aurora CSS10OD034355 · OD · UNIVERSITY OF VIRGINIA · PI WOODFOLK, JUDITH A · 2023 to 2023
$595k
NCI NIH HHS P30 CA044579NIGMS NIH HHS R01 GM132128NIH HHS S10 OD034355
6 · The paper itself

Abstract

Chimeric RNAs resulting from intergenic splicing represent a distinct mechanism for transcriptome expansion. To explore the role of this previously unidentified layer of the transcriptome in sex-specific immunity, we analyzed RNA sequencing data from 425 blood samples and identified a female-specific chimeric RNA,

Indexed as

COVID-19Cyclin-Dependent KinasesRNAEvolution, MolecularFemaleHumansMyeloid CellsRNA SplicingSARS-CoV-2Cyclin-Dependent KinasesRNA

Identifiers

PMID42213831
PMCPMC13220885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.