Evidence map›Paper›PMID 42213392›Full record

ReviewProbiotics and antimicrobial proteins2026

Polymer-Based and Biomaterial Encapsulation of Probiotics for Improved Viability.

Esther Eghogho Omoathebu, Great Iruoghene Edo, Joshua Othuke Orogu, Musa A Said, Raghda S Makia, Ephraim Evi Alex Oghroro, Joseph Oghenewogaga Owheruo, Emad Yousif, Agatha Ngukuran Jikah, Ufuoma Augustina Igbuku and 6 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Esther Eghogho OmoathebuDepartment of Biological and Chemical Sciences, Faculty of Natural Sciences, Michael and Cecilia Ibru University, Ughelli North, Agbarha-Otor, Delta State, Nigeria.
Great Iruoghene EdoDepartment of Chemistry, Faculty of Science, Southern Delta University, Ozoro, Nigeria. greatiruo@gmail.com.
Joshua Othuke OroguDepartment of Microbiology, Faculty of Science, Southern Delta University, Ozoro, Nigeria.
Musa A SaidDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah, 42351, Saudi Arabia.
Raghda S MakiaDepartment of Plant Biotechnology, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq.
Ephraim Evi Alex OghroroDepartment of Chemistry, Faculty of Science, Southern Delta University, Ozoro, Nigeria.
Joseph Oghenewogaga OwheruoDepartment of Food Science and Technology, Faculty of Science, Southern Delta University, Ozoro, Nigeria.
Emad YousifDepartment of Chemistry, College of Sciences, Al-Nahrain University, Baghdad, Iraq.
Agatha Ngukuran JikahDepartment of Pharmacy, Faculty of Pharmacy, Near East University, Nicosia, Cyprus.
Ufuoma Augustina IgbukuDepartment of Chemistry, Faculty of Science, Southern Delta University, Ozoro, Nigeria.
Arthur Efeoghene Athan EssaghahDepartment of Urban and Regional Planning, Faculty of Environmental Sciences, Southern Delta University, Ozoro, Nigeria.
Ibiyinka Agboola FuwapeDepartment of Physics, Michael and Cecilia Ibru University, Agbarha-Otor, Ughelli North, Delta State, Nigeria.
Maryam Rabiu AliyuDepartment of Energy System Engineering, Cyprus International University, TRNC, Mersin 10, Nicosia, 99258, Turkey.
Huzaifa UmarIrfan Suat Gunsel Operational Research Institute, Near East University, TRNC Mersin 10, Nicosia, ZIP: 99138, Turkey.
Dina S AhmedDepartment of Chemical and Petroleum Industries Engineering Techniques, Polytechnic College of Engineering Specializations - Baghdad, Middle Technical University, Baghdad, Iraq.
Ahmed A AlamieryAl-Ayen Scientific Research Center, Al-Ayen Iraqi University, AUIQ, An Nasiriyah, P.O. Box: 64004, ThiQar, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review paper examines various polymers and biomaterials used for probiotic encapsulation, with particular emphasis on how these materials aid in improving probiotic viability. Probiotics are living microorganisms that offer the host a number of beneficial health effects when given in the right amounts to the targeted area of the digestive tract. Despite the array of promised health benefits, the functionality of these probiotics depends on their retaining viability and sufficient cell concentrations at the point of ingestion and digestion. However, a number of factors can compromise the viability of these probiotics, such as pH fluctuations, temperature extremes, oxygen content, flavored additives, moisture activity, packaging and storage conditions. Encapsulation, which is the process of entrapping one substance into another substance, has emerged as an effective strategy to overcome the difficulties associated with preserving probiotic viability. It shields probiotics from extrinsic stressors, while enhancing their stability and promoting efficient delivery to the gut. Probiotic viability during processing, storage, and digesting is ensured by the robust defense against external stressors provided by the polymers and biomaterials utilized to encapsulate these organisms. Their adaptable nature enables incorporation into diverse food systems, such as drinks, baked products, and plant-based formulations, helping to meet the increasing consumer interest in gut health-oriented functional foods. Some biomaterials can also serve as prebiotics, enhancing the proliferation of these beneficial microorganisms. This review aims to highlight the main polymers and biomaterials employed in probiotic encapsulation, with emphasis on how they enhance the stability, functionality, and overall viability of probiotic cells.

Indexed as

BiomaterialsEncapsulationPolymersProbioticsViability

Identifiers

PMID42213392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.