SynthesisLa Radiologia medica2026
Complications of minimally invasive treatments of benign thyroid nodules: preventive andmanaging strategies: A systematic review.
Synthesis in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Efficacy and safety of cooled and uncooled microwave ablation for the treatment of parathyroid adenomas.Irish journal of medical science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeUltrasound (US)-guided thermal ablation (TA) is widely used as a minimally invasive alternative to surgery for symptomatic benign thyroid nodules. Although less invasive, complications occur in up to 4% of cases. This review assessed the incidence of TA-related complications, focusing on prevention and management. MATERIAL AND
methodsPubMed, Embase, and Cochrane were searched for studies on thyroid TA complications. Eligible studies were in English, included > 100 patients, reported complication rates, and had full text available. Studies with malignant nodules, unclear reporting, or < 100 patients were excluded. Risk of bias was assessed with ROBINS-I and evidence certainty with GRADE. Complications and preventive strategies were summarized.
resultsAmong 282 screened studies, 11 including 15,333 patients were analyzed. The pooled overall complication rate was 4.3% (range 1.0-8.8%). Post-procedural pain was most common (1.5%, range 0-5%). Major complications were rare (0.16%), while minor complications occurred in 4.2%. Prevention relied on operator training, knowledge of neck anatomy, hydrodissection, trans-isthmic approach, and moving-shot technique.
conclusionsThyroid TA is safe, with very low major complication rates, though minor events may occur. Best results require strong anatomical knowledge, ultrasound expertise, and correct technique. Evidence quality remains low with moderate-to-serious risk of bias.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.