Evaluation of Ultrasonic-Assisted Aqueous Two-Phase Extraction of Rutin from the Leaves of Moringa oleifera Lam. Through Response Surface Methodology.

Dakalo Lorraine Ndou, Ashwell Rungano Ndhlala, Nikita Tawanda Tavengwa, Ntakadzeni Edwin Madala

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Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Dakalo Lorraine NdouDepartment of Chemistry, Faculty of Science, Engineering and Agriculture, University of Venda, Thohoyandou, South Africa.

Ashwell Rungano NdhlalaGreen Biotechnologies Research Centre, Department of Plant Production, Soil Science and Agricultural Engineering, University of Limpopo, Sovenga, South Africa.

Nikita Tawanda TavengwaDepartment of Chemistry, Faculty of Science, Engineering and Agriculture, University of Venda, Thohoyandou, South Africa.

Ntakadzeni Edwin MadalaDepartment of Biochemistry and Microbiology, Faculty of Science, Engineering and Agriculture, University of Venda, Thohoyandou, South Africa. ntaka.madala@univen.ac.za.

Funding

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6 · The paper itself

Abstract

Rutin, a natural flavonol glycoside prevalent in various fruits and vegetables, is known to possess diverse pharmacological properties. Its extraction from plant materials has been explored through various methods, yielding different outcomes. In the present investigation, UA-ATPE was employed to extract rutin from the leaves of Moringa oleifera, utilizing a 25% saturated salt/ethanol solution to create an aqueous two-phase system. Different salts, such as MgSO

Indexed as

Moringa oleiferaPlant ExtractsPlant LeavesRutinUltrasonicsChromatography, High Pressure LiquidEthanolMagnesium SulfateSodium ChlorideWaterEthanolMagnesium SulfatePlant ExtractsRutinSodium ChlorideWaterAqueous two-phase extractionCentral composite designResponse surface modelRutinUltrasonic

Identifiers

PMID42213320

DOI10.1016/j.indcrop.2018.06.004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.