ReviewMolecular biology reports2026
Harnessing CRISPR-Cas technology for insect pest control: current advances and future perspectives.
Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insect pests pose a significant threat to agriculture, public health, and global biodiversity, prompting the development of innovative control strategies. CRISPR-Cas technology, a revolutionary genome-editing tool, has emerged as a promising approach to tackle these challenges. This review comprehensively explores the current advances in using CRISPR-Cas systems for insect pest control, highlighting key methodologies, successes, and potential hurdles. The fundamental principles of CRISPR-Cas technology, emphasizing its precision and versatility in gene editing, have been outlined. We then delve into various pest-control applications, such as gene drive systems designed to spread genetic modifications through pest populations, thereby reducing their reproductive capacity or increasing their susceptibility to environmental factors. Successful applications of CRISPR-based strategies in insect species such as Aedes aegypti, where gene editing has been used to suppress vector populations and reduce disease transmission potential, and Spodoptera frugiperda, where targeted gene disruption has improved pest management studies, are also highlighted. Furthermore, the ecological and ethical implications of deploying CRISPR-Cas based interventions are discussed, including concerns about unintended consequences, resistance development, and impacts on non-target species. Regulatory frameworks and public acceptance are also examined as critical components for the successful implementation of these technologies. The review concludes with a forward-looking perspective on the future of CRISPR-Cas in pest control, considering advancements in delivery methods, precision editing, and integration with other pest management strategies. We propose potential research directions and highlight the need for interdisciplinary collaboration to optimize the use of CRISPR-Cas technology for sustainable, effective insect pest management. This article serves as a comprehensive resource for researchers, policymakers, and stakeholders, providing a detailed overview of the current state of CRISPR-Cas technology in insect pest control and its future potential to transform pest management practices.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.