ArticlemBio2026
Spermine suppresses
Xiao Wang, Mohua Liu, Xiaoya Qu, Jing Hou, Shukun Chen, Tianyuan Chang, Jiayue Li, Jinglei Xia, Xihui Shen, Yao Wang and 1 more
Abstract read
In one paragraphArticle in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Xiao Wang *Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0009-0003-9433-8271 Mohua Liu *Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Xiaoya Qu *Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Jing HouShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Shukun ChenShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Tianyuan ChangShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Jiayue LiShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Jinglei XiaShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.
Xihui ShenShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0001-6867-8887 Yao WangShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0002-7149-4234 Lei XuShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0002-9886-3677 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Polyamines integrate metabolism with innate immunity; however, their antibacterial roles remain unresolved. Here, we show that spermine suppresses innate immune responses against IMPORTANCE: In our research, we set out to understand how a small, naturally occurring molecule called spermine shapes the first line of defense against
Indexed as
Immunity, InnateMacrophagesMembrane ProteinsNucleotidyltransferasesSalmonella InfectionsSalmonella typhimuriumSpermineToll-Like Receptor 4AnimalscGAS-STING Signaling PathwayCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, BacterialHumansImmune EvasionMiceSignal TransductioncGAS protein, mouseCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, BacterialMembrane ProteinsNucleotidyltransferasesSpermineSting1 protein, mouseSTING ProteinToll-Like Receptor 4cGAS-STING pathwayDNA conformational switchinginnate immune responsemacrophagespolyaminesSalmonella Typhimuriumspermine
Identifiers
PMID42212831
PMCPMC13343856
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