Evidence map›Paper›PMID 42212800›Full record

ArticlemSystems2026

Chromid-like secondary replicons as predicted key sites of biosynthetic gene clusters in

Shuhei Yabe, Yu Zheng, Shunji Takahashi, Chongyang Yang, Yui Nose, Shinichi Yamazaki, Nao Okuma, Mazytha Kinanti Rachmania, Fitria Ningsih, Wellyzar Sjamsuridzal and 3 more

Abstract read
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shuhei YabeRIKEN Center for Sustainable Resource Science, Tsukuba, Japan.ORCID 0000-0002-8581-987X
Yu ZhengRIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.ORCID 0000-0002-1297-8933
Shunji TakahashiRIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.ORCID 0000-0003-1684-9298
Chongyang YangRIKEN Center for Sustainable Resource Science, Tsukuba, Japan.ORCID 0000-0002-2658-2147
Yui NoseRIKEN Center for Sustainable Resource Science, Tsukuba, Japan.
Shinichi YamazakiRIKEN Center for Sustainable Resource Science, Tsukuba, Japan.
Nao OkumaRIKEN Center for Sustainable Resource Science, Tsukuba, Japan.ORCID 0000-0002-1423-9528
Mazytha Kinanti RachmaniaDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.ORCID 0000-0002-5198-3495
Fitria NingsihDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.ORCID 0000-0002-8008-7972
Wellyzar SjamsuridzalDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.ORCID 0000-0003-0794-9510
Mayuko SatoRIKEN Center for Sustainable Resource Science, Yokohama, Japan.ORCID 0000-0002-9876-5612
Kiminori ToyookaRIKEN Center for Sustainable Resource Science, Yokohama, Japan.ORCID 0000-0002-6414-5191
Yasunori IchihashiRIKEN Center for Sustainable Resource Science, Tsukuba, Japan.ORCID 0000-0003-1935-4397

Funding

Institution for Fermentation, Osaka G-2024-1-019Japan Society for the Promotion of Science JP25K01112Japan Society for the Promotion of Science JP25K22374RIKEN TRIP Initiative Field-omicsThe green technologies of excellence program (Gtex) of the Japan Science and Technology Agency JPMJGX23B2
6 · The paper itself

Abstract

Soils harbor immense biosynthetic gene cluster (BGC) diversity that mediates microbial interactions, yet this potential remains unevenly mapped and poorly characterized across diverse bacterial lineages. IMPORTANCE: Soil bacteria produce many of the small molecules that become medicines and help microbes interact with each other. Yet most of this chemical diversity remains unexplored because many soil lineages are difficult to cultivate and remain genomically underrepresented. Much of what we know comes from well-studied groups such as actinomycetes, leaving many soil lineages largely unexplored. We analyzed 183 genomes from

Indexed as

Biosynthetic PathwaysChloroflexiMultigene FamilyRepliconGenome, BacterialMetagenomicsPhylogenySoil Microbiologybiosynthetic gene clusterschromidcomparative genomicsKtedonobacteriasecondary metabolismvolcanic soils

Identifiers

PMID42212800
PMCPMC13289182

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.