Evidence map›Paper›PMID 42212678›Full record

ArticleInfection and immunity2026

Outer membrane vesicles secreted by

Roxanna Barnaby, Amanda Nymon, Paige Salerno, Carolyn T Roche, Young Ah Goo, Byoung-Kyu Cho, Timothy B Gardner, Zdenek Svindrych, Douglas J Taatjes, Thomas H Hampton and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. NontoxigenicMicroorganisms · 2026
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Roxanna Barnaby *Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Amanda Nymon *Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Paige Salerno *Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Carolyn T RocheDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Young Ah GooMass Spectrometry Technology Access Center, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA.
Byoung-Kyu ChoMass Spectrometry Technology Access Center, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA.
Timothy B GardnerCenter for Digestive Health, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Zdenek SvindrychDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, USA.
Douglas J TaatjesDepartment of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont, USA.
Thomas H HamptonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0003-0543-402X
Benjamin RossDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-8817-3138
Bruce A StantonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-1661-407X

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung InfectionsR01HL151385 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2021 to 2024
$2.4M
Mechanisms of adaptation to interbacterial antagonism by the human gut microbiotaR35GM142685 · NIGMS · DARTMOUTH COLLEGE · PI ROSS, BENJAMIN DAVIDSON · 2021 to 2025
$2.0M
Dartmouth Cystic Fibrosis Training ProgramT32HL134598 · NHLBI · DARTMOUTH COLLEGE · PI George A. O'Toole · 2017 to 2026
$1.7M
Cystic Fibrosis Foundation STANTO19G0 STANTO20P0 STANTO23R0 and STANTO19R0NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NHLBI NIH HHS R01 HL151385NHLBI NIH HHS T32 HL134598NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK117469NIGMS NIH HHS R35 GM142685NIH HHS NIH R35GM142685 and CFF ROSS20R3NIH HHS P30 DK020579 UL1 TR002345 P30 CA091842NIH HHS P30-DK117469 (Pilot Project Award) and R01HL151385NIH HHS T32-HL134598.
6 · The paper itself

Abstract

The goals of this study were to develop a model to study host-pathogen interactions in primary human colon organoids and to test the hypothesis that

Indexed as

Bacterial ToxinsBacteroides fragilisChloridesColonCystic Fibrosis Transmembrane Conductance RegulatorMetalloendopeptidasesOrganoidsHost-Pathogen InteractionsHumansBacterial ToxinsBacteroides fragilis toxinCFTR protein, humanChloridesCystic Fibrosis Transmembrane Conductance RegulatorMetalloendopeptidasesBacteroides fragilisCFTRcolon organoidsouter membrane vesiclestransepithelial resistance

Identifiers

PMID42212678
PMCPMC13367044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.