Evidence map›Paper›PMID 42212276›Full record

Trial reportFrontiers in pharmacology2026

Jingfang Granules for prevention of alcohol-induced hangover: a randomized, double-blind, crossover trial in healthy volunteers.

Feng Wu, Yuyang Dai, Siyang Ni, Jing Zhang, Xiaojun Hu, Ying Han, Ying Jiao, Huan Lu, Laichun Lu

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Feng WuNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yuyang DaiNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Siyang NiNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Jing ZhangNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Xiaojun HuNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ying HanNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ying JiaoNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Huan LuNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Laichun LuNational Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Jingfang Granules (JFG), a classical traditional Chinese medicine formula comprising 11 botanical drugs, have traditionally been prescribed to dispel cold and eliminate dampness. This study aimed to clinically evaluate the efficacy and safety of JFG in accelerating alcohol clearance and mitigating hangover symptoms. Methods: A randomized, double-blind, two-period crossover trial enrolled 48 healthy adults. Participants received JFG (6 sachets × 15 g) or placebo 30 min before consuming 100 mL of 56% ABV baijiu within 10 min. Primary endpoints were plasma alcohol concentrations measured up to 24 h post-consumption. Secondary endpoints included plasma alcohol AUC Results: JFG significantly reduced plasma alcohol concentrations from 30 min to 8 h after consumption (P < 0.005) and decreased plasma alcohol AUC Discussion: JFG significantly reduced plasma alcohol levels for up to 8 h after consumption and showed a trend toward lower hangover symptom scores; however, the mechanism remains unknown. Clinical Trial Registration: https://www.chictr.org.cn/, identifier ChiCTR2400084155.

Indexed as

alcoholhangoverJingfang Granulesrandomized controlled trialtraditional Chinese medicine

Identifiers

PMID42212276
PMCPMC13212316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.