Evidence map›Paper›PMID 42212250›Full record

ArticleJournal of stem cells & regenerative medicine2026

Intraoperative Intramedullary Photobiomodulation Therapy for Consolidation of Atypical Femoral Fractures in Elderly Women: A Pilot Study.

Daniel Oksman, Gabrielly Santos Pereira, Andre Carvalho Rodriguez, Maria Aparecida Dalboni, Marcelo Lourenco da Silva, Maria Cristina Chavantes

Abstract read
In one paragraph

Article in Journal of stem cells & regenerative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel OksmanDepartment of Orthopedics and Traumatology, Prevent Senior Institute, São Paulo, SP, Brazil.
Gabrielly Santos PereiraLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), UNIFAL-MG, Alfenas, MG, Brazil.
Andre Carvalho RodriguezMedicine Postgraduation Program, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Maria Aparecida DalboniMedicine Postgraduation Program, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Marcelo Lourenco da SilvaLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), UNIFAL-MG, Alfenas, MG, Brazil.
Maria Cristina ChavantesMedicine Postgraduation Program, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atypical femoral fractures (AFFs) are rare complications often linked to prolonged bisphosphonate use. This pilot study evaluated the feasibility of intraoperative intramedullary photobiomodulation therapy (PBMT) using long, sterile optical fibers during surgical fixation. Methods: Eleven elderly female patients with AFFs were randomized into a PBMT-treated group or control. PBMT was applied using a red laser (638 nm, 3.2 J per point). Results: No statistically significant differences in healing, complications, or function were observed. However, a trend toward improved RUSTm scores in the PBMT group emerged. Conclusion: This novel technique appears feasible and safe; further studies are needed to assess its regenerative potential.

Indexed as

Atypical FracturesLow-Level Laser Therapy (LLLT)Orthopedic Surgery

Identifiers

PMID42212250
PMCPMC13214507

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.