ArticleJournal of stem cells & regenerative medicine2026
Simple Custom Led Panel increases Adipogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells through Photobiomodulation.
Article in Journal of stem cells & regenerative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- From Photosynthesis to Photobiomodulation: Expanding the Therapeutic Potential of Light.Journal of stem cells & regenerative medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Impaired proliferation and differentiation capacity of adipose-derived mesenchymal stem cells (AD-MSCs) in obesity hinder the formation of metabolically healthy adipocytes, thereby aggravating metabolic disorders. Photobiomodulation (PBM) is a simple, non-invasive light-based therapy that primarily uses red and near-infrared light and has been shown to enhance the proliferation and differentiation potential of stem cells, including AD-MSCs. However, the wide variation in PBM parameters used in previous studies necessitates further investigation to determine optimal dosage and delivery methods. This study aimed to construct a simple, easy-to-assemble LED panel for PBM application and to identify an effective dose that stimulates proliferation and adipogenic differentiation of AD-MSCs. Methods: The panel delivered 1 J/cm Results: No significant differences in total cell count or viability were observed among the groups, indicating that the PBM protocol is safe. KI-67 expression was similar between the P1Pro and control groups (Control: 1.00 ± 0.02; P1Pro: 1.19 ± 0.06, p > 0.05), whereas the P2Pro group showed a significant decrease compared with P1Pro (P2Pro: 0.71 ± 0.06, p = 0.02). The P1Diff group also exhibited a significant increase in expression of adipogenic markers PPARꙋ and CEBPα (1.55 ± 0.04, p < 0.01 and 2.9 ± 0.3, p < 0.01, respectively), while the P2Diff group showed minimal to no difference compared with the control. Conclusion: Although further studies are required to assess PBM effects on dysfunctional AD-MSCs from obese individuals, this study demonstrates that a simple, easy-to-assemble PBM device can safely and effectively enhance the proliferation and differentiation capacity of AD-MSCs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.