Evidence map›Paper›PMID 42212170›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Performance evaluation of biological safety cabinets: a real-world analysis.

Tao Song, Shaohua Yin, Zhenlin Liu, Xiaoqi Xue, Yilin Li, Yong Li, Xingshuo Zhang, Xiangyun Qiao, Chenglin Wu, Han Zhang and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Tao Song *Department of Medical Engineering, Peking University Third Hospital, Beijing, China.
Shaohua Yin *Department of Medical Engineering, Peking University Third Hospital, Beijing, China.
Zhenlin Liu *Department of Medical Engineering, Peking University Third Hospital, Beijing, China.
Xiaoqi XueDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Yilin LiDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Yong LiDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Xingshuo ZhangDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Xiangyun QiaoDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Chenglin WuDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Han ZhangDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Rongxi JiaDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Xiaoming LiuDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Zhe SunDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Wei YaoDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Bo ZhangDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Feng XuDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Yun TianDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.
Jin TianDepartment of Medical Engineering, Peking University Third Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Biological safety cabinets (BSCs) are essential for protecting personnel, samples, and the environment in clinical and research laboratories. Evidence on the real-world performance of Class II BSCs in China remains limited, particularly regarding differences between domestic and imported equipment. Methods: We conducted a cross-sectional evaluation of 360 Class II BSCs in Beijing using 1,803 performance testing records from 2018 to 2023. Performance indicators, including noise, illumination, cleanliness, inflow velocity, downflow velocity, HEPA filter integrity, and airflow smoke pattern were measured according to JG 170-2005, YY 0569-2011 and SN/T 3901-2014 standards. BSCs were assessed and classified as fully qualified performance (FQP) if the indicator met the standard without equaling the threshold, marginally qualified performance (MQP) if the indicator equaled the threshold, or unqualified if the standard was not met. Qualified rates were compared by manufacturing region, hospital level, using sector, and service life using Results: Among 360 Class II BSCs, the median service life was 7 years (IQR 5-10). The overall qualified rate was 70.4%, with no difference between domestic and imported BSCs (71.3% Discussion: These findings suggest that BSC reliability reflects an interplay between manufacturing-related characteristics and in-use performance, and that the MQP helps identify BSCs operating near minimum safety margins for proactive monitoring and timely intervention.

Indexed as

biological safety cabinetcross-sectional studylaboratory safetymarginally qualified performancemedical and health institution

Identifiers

PMID42212170
PMCPMC13212249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.