ReviewStructural heart : the journal of the Heart Team2026
State-of-the-Art Review: Transjugular Tricuspid Valve Replacement Using the LuX-Valve Plus System.
Review in Structural heart : the journal of the Heart Team, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Transjugular LuX-Valve Plus transcatheter tricuspid valve replacement for torrential tricuspid regurgitation in a patient with a giant right atrium and multiple prior valve interventions: a case report.European heart journal. Case reports · 2026Article
- The pitfalls of transcatheter tricuspid valve repair: what we have learned in our last decade of experience.Annals of cardiothoracic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe tricuspid regurgitation remains a major therapeutic challenge, particularly in patients with extensive annular dilation or advanced right heart remodeling. Transcatheter tricuspid valve replacement(TTVR) has emerged as a promising alternative for anatomically complex and high‑risk patients who are not suitable for surgery or transcatheter edge‑to‑edge repair. Among currently available systems, the LuX‑Valve Plus device offers a unique transjugular approach and anchoring strategy. This state‑of‑the‑art review provides a comprehensive overview of the LuX‑Valve Plus system, including technical characteristics, procedural steps, multimodality imaging guidance, and key anatomical considerations for patient selection. Drawing on current literature and expert experience, the review describes a step‑by‑step procedural framework with a focus on anatomical screening, computed tomography-based planning, intraprocedural three‑dimensional transesophageal echocardiography, and the use of advanced imaging modalities such as fusion imaging. Practical tips are provided to optimize device positioning, septal anchoring, and leaflet interaction in the setting of highly variable anatomy. Overall, the LuX‑Valve Plus system broadens the spectrum of TTVR to anatomically challenging patients, and this review offers a practical guide for clinicians by offering detailed technical insights, imaging protocols, and procedural strategies essential for successful implantation and avoidance of complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.