ArticleJCEM case reports2026
Severe hypocalcemia in a patient with extensive cranial Paget disease: a diagnostic challenge.
Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paget disease of bone (PDB) is a focal disorder of accelerated bone remodeling that typically presents with bone pain, deformity, or elevated alkaline phosphatase (ALP). Clinically significant hypocalcemia is uncommon and is usually associated with vitamin D deficiency and high bone turnover states. We report a 64-year-old woman who presented with altered mental status and severe hypocalcemia (total calcium 4.1 mg/dL [International System of Units (SI): 1.0 mmol/L]; reference range 8.5-10.1 mg/dL [SI: 2.1-2.5 mmol/L]) and markedly elevated ALP (1550 U/L; reference range 35-104 U/L). She had a history of progressive cranial enlargement and bilateral hearing loss. Laboratory evaluation revealed profound vitamin D deficiency. Skull radiography demonstrated extensive calvarial thickening with a classic "cotton wool" appearance, and bone scintigraphy showed intense tracer uptake throughout the cranial bones.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.