ArticleJournal of the American Statistical Association2026
Bayesian Image Mediation Analysis.
Article in Journal of the American Statistical Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Elevated neurofilament light levels in acute anorexia nervosa are associated with alterations in white matter volume and connectivity networks.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Mediation analysis aims to separate the indirect effect through mediators from the direct effect of the exposure on the outcome. It is challenging to perform mediation analysis with neuroimaging data which involves high dimensionality, complex spatial correlations, sparse activation patterns and relatively low signal-to-noise ratio. To address these issues, we develop a new spatially varying coefficient structural equation model for Bayesian Image Mediation Analysis (BIMA). We define spatially varying mediation effects within the potential outcomes framework, employing a soft-thresholded Gaussian process prior for functional parameters. We establish posterior consistency for spatially varying mediation effects along with selection consistency on important regions that contribute to the mediation effects. We develop an efficient posterior computation algorithm scalable to analysis of large-scale imaging data. Through extensive simulations, we show that BIMA can improve the estimation accuracy and computational efficiency for high-dimensional mediation analysis over existing methods. We apply BIMA to analyze behavioral and fMRI data in the Adolescent Brain Cognitive Development (ABCD) study with a focus on inferring the mediation effects of the parental education level on the children's general cognitive ability that are mediated through the working memory brain activity. Supplementary materials for this article are available online, including a standardized description of the materials available for reproducing the work.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.