Evidence map›Paper›PMID 42211734›Full record

ArticleAquaculture nutrition2026

Size-Dependent Efficacy of Lipid Nanoparticles in Improving Glucose Utilization of Largemouth Bass (

Kaipeng Zhang, Tengfei Zhu, Yamin Wang, Jing Chen, Shan Xie, Zhenye Lin, Xiaotong Chen, Yingying Yu, Yining Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aquaculture nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaipeng ZhangSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0009-0002-2607-9549
Tengfei ZhuSouth China Sea Fisheries Research Institute, Key Laboratory of South China Sea Fishery Resources Exploitation and Utilization, Ministry of Agriculture and Rural Affairs, Chinese Academy of Fishery Sciences, Guangzhou, 510300, Guangdong, China, cafs.ac.cn.ORCID https://orcid.org/0009-0001-5379-6503
Yamin WangSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0009-0005-4792-8572
Jing ChenSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0009-0009-3487-1027
Shan XieSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0009-0006-5748-3869
Zhenye LinSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0009-0008-4325-8200
Xiaotong ChenSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0009-0000-5344-4025
Yingying YuSchool of Animal Science and Technology, Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan University, Foshan, 528225, Guangdong, China, fosu.edu.cn.ORCID https://orcid.org/0000-0002-8199-3125
Yining XuDepartment of Pharmacy, Institute of Metabolic Diseases and Pharmacotherapy, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China, scu.edu.cn.ORCID https://orcid.org/0000-0001-6201-9338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds: Largemouth bass ( Objective: LNPs were evaluated as novel potential additives to enhance the glucose utilization in Methods: We constructed LNPs to serve as a feed additive for modulating the glucose metabolism in Results: HG exposure activated the hepatic PI3K/AKT pathway, upregulated the expression of gluconeogenesis-related genes ( Conclusion: 150 nm LNPs effectively ameliorate high-carbohydrate-induced metabolic damage by targeting GLUT5 to enhance intestinal glucose absorption and regulating the PI3K/AKT-gluconeogenesis/glycogenesis cascade, providing a targeted solution for improving HG feed utilization in carnivorous fish aquaculture.

Indexed as

aquaculture productionfeed additivesgene expressionglucose metabolismhigh carbohydrate feedlargemouth bassnanotechnology

Identifiers

PMID42211734
PMCPMC13213335

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.