Evidence map›Paper›PMID 42211645›Full record

ArticleCureus2026

A Call for Vigilance: Trigeminocardiac Reflex Presenting As Ventricular Bigeminy During Marginal Mandibulectomy.

Bheemas Atlapure, Dharitri Dutta, Habib Md R Karim, Satheesh Gunashekar, Anirban Bhattacharjee

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bheemas AtlapureAnaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences, Guwahati, IND.
Dharitri DuttaAnaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences, Guwahati, IND.
Habib Md R KarimAnaesthesiology, Critical Care, and Pain Medicine, All India Institute of Medical Sciences, Guwahati, IND.
Satheesh GunashekarAnaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences, Guwahati, IND.
Anirban BhattacharjeeAnaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences, Guwahati, Assam, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trigeminocardiac reflex (TCR) is an autonomic reflex elicited by stimulation of the trigeminal nerve and is most commonly characterized by bradycardia and hypotension. In oral and maxillofacial surgery, peripheral TCR may occur during manipulation of the maxillary or mandibular divisions, occasionally presenting with atypical cardiovascular responses. We report a rare case of peripheral TCR manifesting as sudden severe hypertension with ventricular bigeminy during wide local excision and marginal mandibulectomy in a 69-year-old male with carcinoma of the lower alveolus. The hemodynamic disturbance coincided with the traction and suturing of the mandibular alveolar margin and was refractory to pharmacological management. Prompt release of surgical traction resulted in immediate resolution of both hypertension and arrhythmia, with no postoperative cardiac sequelae. This case underscores the importance of recognizing atypical presentations of TCR in maxillofacial procedures and highlights the need for close anesthetic-surgical communication and gentle tissue handling to prevent potentially life-threatening complications.

Indexed as

cardiac arrhythmiasmandibulectomyoral surgical procedurestrigeminal nervetrigeminocardiac reflexventricular bigeminy

Identifiers

PMID42211645
PMCPMC13213701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.