ArticleCureus2026
Neuropsychiatric Effects of Oseltamivir in an Older Adult With End-Stage Renal Disease: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Oseltamivir is a renally cleared antiviral medication that is highly effective and often prescribed for influenza prophylaxis in nursing home (NH) settings. We present the case of a 74-year-old man with a history of end-stage renal disease (ESRD) on hemodialysis (HD) and vascular dementia who received prophylactic oseltamivir during an influenza outbreak at his NH and subsequently developed acute neuropsychiatric symptoms. A comprehensive work-up for an acute reversible cause was not identified other than the introduction of the new medication, oseltamivir. The patient's symptoms resolved after cessation of the medication. To our knowledge, we are the first to report a case of oseltamivir-induced delirium in an older adult receiving ESRD-dosed prophylactic oseltamivir. Our case highlights the need for providers to be vigilant regarding the potential neuropsychiatric side effects of oseltamivir among older adults receiving influenza prophylaxis. Older adults living with ESRD or dementia may be particularly vulnerable.
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